摘要
目的:评价耳穴疗法治疗以胃脘痛为主症的消化系统疾病的有效性及安全性。方法:检索PubMed、EMbase、the Cochrane Library、中国知网、万方数据库、维普数据库、中国生物医学文献数据库建库至2023年3月有关耳穴疗法治疗以胃脘痛为主要症状的随机对照试验(RCT),采用RevMan 5.4软件进行Meta分析。结果:最终纳入24篇文献,涉及1927例病人。Meta分析结果显示,耳穴疗法治疗胃脘痛的总有效率高于对照组[RR=1.19,95%CI(1.12,1.26),P<0.00001],其中,耳穴贴压治疗胃脘痛的有效率优于常规治疗[RR=1.13,95%CI(1.02,1.24),P=0.02]、中药汤剂治疗[RR=1.26,95%CI(1.15,1.38),P<0.00001]、单纯西药治疗[RR=1.18,95%CI(1.11,1.25),P<0.00001];经皮耳迷走神经电刺激治疗胃脘痛的有效率优于经皮耳非迷走神经电刺激[RR=1.37,95%CI(1.15,1.63),P=0.0005];耳穴疗法降低中医证候症状评分[SMD=-1.49,95%CI(-2.02,-0.95),P<00001]、血清胃泌素[SMD=-0.63,95%CI(-1.03,-0.23),P=0.002]及改善疼痛症状[SMD=-0.89,95%CI(-1.14,-0.64),P<0.00001]优于对照组,差异有统计学意义。安全性评价提示耳穴疗法未见明显不良反应。结论:现有证据表明,耳穴疗法可有效改善以胃脘痛为主症的胃肠症状,不良反应小,但结论仍需更多高质量、多中心、大样本的随机对照试验进一步验证。
Objective:To evaluate the effectiveness and safety of ear acupoint therapy in the treatment of digestive system diseases mainly characterized by epigastric pain.Methods:RCT related to ear acupoint therapy for treating epigastric pain was retrieved from PubMed,EMbase,the Cochrane Library,CNKI,WanFang Database,VIP,and CBM.The search deadline was from the establishment of each database to March 2023.RevMan 5.4 software was adopted for data analysis.Results:A total of 24 articles were ultimately included,involving 1927 patients.The Meta-analysis results showed that the total effective rate of ear acupoint therapy for treating epigastric pain was higher than that of the control group(RR=1.19,95%CI 1.12-1.26,P<0.00001).Among them,the effective rate of ear acupoint pressing therapy for epigastric pain was better than conventional treatment(RR=1.13,95%CI 1.02-1.24,P=0.02),traditional Chinese medicine decoction treatment(RR=1.26,95%CI 1.15-1.38,P<0.00001),and simple Western medicine treatment(RR=1.18,95%CI 1.11-1.25,P<0.00001).The effective rate of transcutaneous vagus nerve electrical stimulation in the treatment of epigastric pain was better than that of non vagus nerve electrical stimulation(RR=1.37,95%CI 1.15-1.63,P=0.0005)..Ear acupoint therapy was superior to the control group in reducing traditional Chinese medicine syndrome score(SMD=-1.49,95%CI-2.02--0.95,P<00001),serum gastrin(SMD=-0.63,95%CI-1.03--0.23,P=0.002),and improving pain symptoms(SMD=-0.89,95%CI-1.14--0.64,P<0.00001),with statistically significant differences.The safety evaluation indicated that there were no significant adverse reactions observed with ear acupoint therapy.Conclusion:Existing evidence suggests that ear acupoint therapy can effectively improve gastrointestinal symptoms,mainly characterized by epigastric pain,with minimal adverse reactions.However,more high-quality,multicenter,and large sample randomized controlled trials are still needed to further validate this conclusion.
作者
龙远玉
熊江艳
粟周云
夏丽桃
杨舒婷
马四补
LONG Yuanyu;XIONG Jiangyan;SU Zhouyun;XIA Litao;YANG Shuting;MA Sibu(Guizhou University of Traditional Chinese Medicine,Guizhou 550025 China)
出处
《循证护理》
2024年第6期975-983,共9页
Chinese Evidence-Based Nursing
关键词
耳穴疗法
胃脘痛
慢性胃炎
有效性
META分析
循证护理
auricular acupoint therapy
epigastric pain
chronic gastritis
effectiveness
Meta-analysis
evidence-based nursing
作者简介
龙远玉,护士,硕士研究生在读;通讯作者:熊江艳,E-mail:522305656@qq.com。
