摘要
目的:探讨妊娠合并特发性血小板减少性紫癜(ITP)的危险因素及护理对策.方法:选取2020年1月至2022年12月本院收治的56例妊娠合并ITP的孕妇为研究对象并将其纳入ITP组(n=56);另选取同一时期在本院行正常产前检查的56例妊娠未合并ITP的孕妇纳入对照组(n=56).分析两组研究对象的临床资料,比较其产次、孕龄、血小板计数(BPC)、平均血小板体积(MPV)、血小板分布宽度(PDW)、血小板-大细胞比率(P-LCR)、凝血酶原时间(PT)、活化部分凝血活酶时间(aPTT)、纤维蛋白原(Fbg)、凝血因子Ⅷ活性(FⅧ:C)等.采用多因素非条件Logistic回归法分析影响孕妇妊娠合并ITP的危险因素,并制定相应的护理对策.结果:ITP组BPC水平低于对照组,PT、aPTT短于对照组,MPV、PDW、P-LCR、Fbg及FⅧ:C水平和产次≥2次占比均高于对照组,差异均有统计学意义(P<0.05).多因素非条件Logistic回归法分析显示,产次≥2次、BPC水平过低、aPTT缩短以及MPV、Fbg和P-LCR水平过高,均为导致妊娠合并ITP发生的独立危险因素(OR>1,P<0.05).结论:产次≥2次,血小板相关参数及凝血功能状态异常,均为影响妊娠合并ITP的独立危险因素,医护人员应密切关注该类患者BPC和凝血功能变化,制定针对性的干预措施.
Objective:To explore risk factors of pregnancy combined with idiopathic thrombocytopenic purpura(ITP)and its nursing countermeasures.Methods:A total of 56 pregnant women with ITP treated in our hospital between January 2020 and December 2022 were selected as study subjects,and included in the ITP group(n=56).Another 56 pregnant women who underwent normal prenatal examinations in our hospital during the same period and did not have ITP were selected as the control group(n=56).The clinical data of the two groups were analyzed.The parity,gestational age,blood platelet count(BPC),mean platelet volume(MPV),platelet distribution width(PDW),platelet-large cell ratio(P-LCR),prothrombin time(PT),activated partial thromboplastin time(aPTT),fibrinogen(Fbg)and coagulation factor VII activity(FVII:C)were compared between the two groups.The risk factors of pregnancy combined with ITP were analyzed by multivariate unconditional logistic regression analysis,and the corresponding nursing countermeasures were made.Results:Compared with control group,BPC was lower,PT and aPTT were shorter,and levels of MPV,PDW,P-LCR and the proportion of parity≥2 times were higher in ITP group,the differences were statistically significant(P<0.05).Logistic regression analysis showed that parity≥twice,low BPC and aPTT,high MPV,Fbg and P-LCR were independent risk factors of pregnancy combined with ITP(OR>1,P<0.05).Conclusion:Parity≥2,abnormal platelet related parameters and coagulation function status are independent risk factors of pregnancy combined with ITP.Medical staffs should pay close attentions to the changes of BPC and coagulation function in patients and formulate targeted intervention measures.
作者
陈西西
郝晶
唐姗
屠朝霞
CHEN Xi-xi;HAO Jing;TANG Shan;TU Zhao-xia(Department of Obstetrics,the First People's Hospital of Shangqiu,Shangqiu 476005,China)
出处
《四川解剖学杂志》
2023年第4期126-128,共3页
Sichuan Journal of Anatomy
作者简介
陈西西,护师,本科学历,研究方向:产科护理,e-Mail:cxx15082921917@163.com。
