摘要
经皮冠状动脉介入术(percutaneous coronary intervention,PCI)是目前最有效的再灌注方式,但心肌梗死(myocardial infarction,MI)患者在术后发生不良心血管事件的风险仍然较高,这种现象与冠脉微循环障碍(coronary microvascular dysfunction,CMD)密切相关。目前已提出很多诊疗策略防治冠脉微循环障碍,但常规西药治疗效果并不显著,不良心血管事件的发生率居高不下,仍缺乏有效的治疗方案。多项研究表明,中药对冠状动脉介入术后冠脉微循环障碍有显著疗效。概述中医药治疗冠状动脉介入术后冠脉微循环障碍的相关研究进展,以期为冠状动脉介入术后冠脉微循环障碍提供新的治疗思路。
Percutaneous coronary intervention(PCI)is currently the most effective reperfusion method,but the patients with myocardial infarction(MI)are still at high risk of adverse cardiovascular events after PCI surgery.This phenomenon is closely related to coronary microvascular dysfunction(CMD).Many diagnosis and treatment strategies have been proposed,but the effect of conventional western medicine treatment is not significant.The incidence of major adverse cardiovascular events remains high,and there is still a lack of effective treatment plan.A number of studies have shown that traditional Chinese medicine has a significant effect on postoperative microcirculation disease after PCI.This article summarized the relevant mechanism of traditional Chinese medicine in the treatment of CMD after PCI in order to provide new treatment ideas for CMD after PCI surgery.
作者
王澳龙
卫靖靖
于瑞
彭广操
李兴渊
朱明军
WANG Aolong;WEI Jingjing;YU Rui;PENG Guangcao;LI Xingyuan;ZHU Mingjun(Henan University of Chinese Medicine,Zhengzhou 450000,Henan,China;The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,Henan,China)
出处
《中华中医药学刊》
CAS
北大核心
2024年第2期136-141,共6页
Chinese Archives of Traditional Chinese Medicine
基金
国家重点研发计划-中医药现代化专项(2019YFC1710001,2019YFC1710000)
国家自然科学基金重点项目(82030120)
河南省中医药科学研究专项(2018JDZX009)。
关键词
经皮冠状动脉介入
冠脉微循环障碍
中医药
percutaneous coronary intervention
coronary microvascular dysfunction
traditional Chinese medicine
作者简介
王澳龙(1999-),男,河南许昌人,硕士在读,研究方向:中西医结合心血管疾病的预防和治疗;通讯作者:朱明军(1964-),男,河南新乡人,主任医师、教授,博士研究生导师,研究方向:中西医防治心血管疾病的临床和基础。E-mail:zhumingjun317@163.com。