摘要
本研究旨在评估饲粮中添加博落回散对泰和乌骨鸡生长性能、屠宰性能、器官指数、血清生化指标、肠道形态以及主要活性成分血根碱和白屈菜红碱在组织中的残留。选取1日龄健康状况良好、体重相近的泰和乌骨鸡200只,随机分为2组,每组10个重复,每个重复10只鸡,对照组饲喂基础饲粮,博落回散组饲喂添加500 mg/kg博落回散的饲粮,连续饲喂56 d。试验结果表明:(1)与对照组相比,饲粮中添加博落回散可显著提高泰和乌骨鸡平均日增重和试验末重,分别提高6.00%和9.72%(P<0.05),料重比显著降低5.29%(P<0.05)。(2)与对照组相比,饲粮中添加博落回散可显著降低泰和乌骨鸡血清尿素氮水平,降低22.06%(P<0.05)。(3)与对照组相比,饲粮中添加博落回散可显著降低泰和乌骨鸡十二指肠绒隐比,降低20.41%(P<0.05)。(4)使用超高效液相色谱-串联三重四极杆质谱未在心、肝、脾、肾、胸肌、腿肌、皮肤和脂肪等组织中检测到博落回散中血根碱和白屈菜红碱的残留(低于定量限2μg/L和0.5μg/L)。综上,饲粮中长期添加500 mg/kg博落回散可提高泰和乌骨鸡的生长性能,降低血清尿素氮水平,改善小肠形态结构,且无组织残留风险。
This experiment was conducted to study the effects of dietary Boluohui San on growth performance,slaughter performance,organ coefficient,serum biochemical indices,intestinal morphology and residues of sanguinarine and chelerythrine in tissues of Taihe silky fowls.A total of 200 healthy 1-day-old Taihe silky fowls with similar body weight were randomly divided into 2 groups with 10 replicates per group and 10 chickens per replicate.The control group were fed a basal diet without antibiotics,and Boluohui San group were fed the basal diet supplemented with 500 mg/kg Boluohui San.The experiment lasted for 56 days.The results showed as follows:(1)Compared with the control group,the addition of Bolusan in the diet significantly increased the average daily weight gain and the end weight of the test in Taihe silky fowls by 6.00%and 9.72%respectively(P<0.05),and significantly reduced the feed-to-weight ratio by 5.29%(P<0.05).(2)Compared with the control group,the addition of Boluohui San in the diet significantly reduced the content of blood urea nitrogen(BUN)of Taihe silky fowls by 22.06%(P<0.05).(3)Compared with the control group,the addition of Boluohui San in the diet significantly reduced villus hight to crypt depth ratio of the duodenum of Taihe silky fowls by 20.41%(P<0.05).(4)After the experiment,no residual sanguinarine and chelidonine were detected in heart,liver,spleen,kidney,chest muscle,leg muscle,skin and adipose tissue of Taihe silky fowls(Below the detection limit of 2μg/L and 0.5μg/L),using ultra performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS).In conclusion,basal diets supplemented with 500 mg/kg Boluohui San could improve growth performance,decrease BUN content,and improve the small intestinal morphology of Taihe silky fowls,and there was no risk of tissue residue.
作者
李嘉鸣
刘梦婷
董朕
刘华
邹湘霖
杨子辉
陈杰
曾建国
张明军
LI Jiaming;LIU Mengting;DONG Zhen;LIU Hua;ZOU Xianglin;YANG Zihui;CHEN Jie;ZENG Jianguo;ZHANG Mingjun(College of Veterinary Medicine,Hunan Agricultural University,Changsha,Hunan Province 410128,China;College of Animal Science and Technology,Hunan Agricultural University,Changsha,Hunan Province 410128,China;Key Laboratory of Chinese Veterinary Medicine in Hunan Province,Hunan Agricultural University,Changsha,Hunan Province 410128,China;Guangzhou xiangfeng breeding co.,ltd,Guangzhou,Guangdong Province 510800,China)
出处
《中国饲料》
北大核心
2024年第3期76-82,共7页
China Feed
基金
现代农业产业技术体系建设专项资金(CARS-21)
湖南省重点研发计划(2020NK2031)。
关键词
博落回散
泰和乌骨鸡
残留
生长性能
Boluohui San
Taihe silky fowls
residue
growth performance
作者简介
李嘉鸣,硕士,研究方向为药代动力学及兽药残留,E-mail:joummylee@163.com;通讯作者:张明军,副教授,研究方向为中兽医临床诊疗,E-mail:zhmj6997@163.com;通讯作者:曾建国,教授,研究方向为中药资源研究与中兽药创制,E-mail:zengjianguo@hunau.edu.cn。
