摘要
目的探讨多烯磷脂酰胆碱配合胆宁片对酒精性脂肪肝患者临床症状与肝功能的影响。方法将80例酒精性脂肪肝患者随机分为两组各40例。对照组应用多烯磷脂酰胆碱治疗,观察组采用多烯磷脂酰胆碱配合胆宁片治疗。比较两组的治疗效果、肝功能及不良反应发生率。结果观察组治疗总有效率为95.00%,高于对照组的80.00%(P<0.05)。治疗后,观察组AST、ALT、TBil、GGT、MCV水平均低于对照组(P<0.05)。两组不良反应发生率无统计学差异(P>0.05)。结论多烯磷脂酰胆碱配合胆宁片治疗酒精性脂肪肝患者的效果较好,能够改善患者的肝功能,安全性较高,值得推广应用。
Objective To explore the impact of polyene phosphatidylcholine combined with Danning tablets on clinical symptoms and liver function in patients with alcoholic fatty liver.Methods 80 cases of patients with alcoholic fatty liver were randomly divided into two groups,with 40 cases in each group.The control group was treated with polyene phosphatidylcholine,and the observation group was treated with polyene phosphatidylcholine combined with Danning tablets.The treatment effect,liver function,and incidence of adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 95.00%,higher than 80.00%in the control group(P<0.05).After treatment,the liver function and MCV levels of the observation group were lower than those of the control group(P<0.05).No statistical difference was found in the incidence of adverse reactions between the two groups(P>0.05).Conclusions Polyene phosphatidylcholine combined with Danning tablets in the treatment of patients with alcoholic fatty liver has better effect,can improve the liver function,with higher medication safety,which is worthy of promotion and application.
作者
张嫣
王静
郑晓永
ZHANG Yan;WANG Jing;ZHENG Xiaoyong(Department of Gastroenterology,the Third People's Hospital of Henan Province,Zhengzhou 450006,China)
出处
《临床医学工程》
2024年第1期61-62,共2页
Clinical Medicine & Engineering
关键词
多烯磷脂酰胆碱
胆宁片
酒精性脂肪肝
临床症状
肝功能
Polyene phosphatidylcholine
Danning tablets
Alcoholic fatty liver
Clinical symptom
Liver function
作者简介
张嫣(1985-),女,河南郑州人,硕士研究生学历,主治医师,从事消化内科临床工作。
