摘要
目的:观察脑灌注CT成像在早期脑梗死诊断及预后评估中的应用价值。方法:回顾性选取2019年2月—2022年3月于萍乡市人民医院收治的80例脑梗死患者临床资料。所有患者均行脑灌注CT成像检查,比较发生脑梗死患侧与对侧正常组织的脑灌注CT成像参数。治疗1个月后,评估预后效果,将其分为预后良好组和预后不良组,并比较两组脑灌注CT成像参数并分析脑梗死预后的影响因素。结果:脑梗死患者患侧脑血容量(CBV)、脑血流量(CBF)均明显低于对侧正常组织,平均通过时间(MTT)、达峰时间(TTP)均明显高于对侧正常组织(P<0.05)。预后良好组与预后不良组间年龄、性别、饮酒史、吸烟史、冠心病、高血压、房颤、高密度脂蛋白胆固醇(HDL-C)及低密度脂蛋白胆固醇(LDL-C)比较,差异均无统计学意义(P>0.05);预后良好组和预后不良组美国国立卫生研究院卒中量表(NIHSS)评分、最终梗死体积、同型半胱氨酸(Hcy)、空腹血糖(FBG)、CBV、CBF、TTP、MTT水平比较,差异均有统计学意义(P<0.05)。对有统计学意义的指标进一步行logistic回归分析,结果显示NIHSS分数高、最终梗死体积大、FBG、MTT、TTP水平高及CBV、CBF水平低为脑梗死患者预后不良的独立危险因素(P<0.05)。结论:对早期脑梗死患者进行脑灌注CT成像具有一定的诊断应用价值,可评估患者预后,为临床治疗提供一定依据,同时可依据最终梗死体积进一步预测患者预后。
Objective:To observe the application value of cerebral perfusion CT imaging in the diagnosis and prognosis of early cerebral infarction.Method:Clinical data of 80 patients with cerebral infarction admitted to Pingxiang People's Hospital from February 2019 to March 2022 were retrospectively selected.All patients underwent cerebral perfusion CT imaging examination,and the parameters of cerebral perfusion CT imaging in the the affected side of cerebral infarction and the contralateral normal tissues were compared.After 1 month of treatment,the prognostic effect was assessed,and they were divided into good prognosis group and poor prognosis group,and the cerebral perfusion CT imaging parameters of the two groups were compared and the influencing factors of cerebral infarction prognosis were analyzed.Result:Cerebral blood volume(CBV)and cerebral blood flow(CBF)of the affected side were significantly lower than those of the contralateral normal tissues,and mean transit time(MTT)and time to peak(TTP)of the patients were significantly higher than those of the contralateral normal tissues(P<0.05).There were no statistically significant differences in age,gender,drinking history,smoking history,coronary heart disease,hypertension,atrial fibrillation,high-density lipoprotein cholesterol(HDL-C),and low-density lipoprotein cholesterol(LDL-C)between the good prognosis group and the poor prognosis group were compared(P>0.05);the national institutes of health stroke scale(NIHSS)score,final infarct volume,homocysteine(Hcy),fasting blood glucose(FBG),CBV,CBF,TTP,and MTT levels between the good prognosis group and the poor prognosis group were compared,the differences were statistically significant(P<0.05).Further logistic regression analysis was performed on statistically significant indicators,and the results showed high NIHSS score,large final infarct volume,high FBG,MTT,TTP levels,and low CBV,CBF level were independent risk factors for the poor prognosis of patients with cerebral infarction(P<0.05).Conclusion:Cerebral perfusion CT imaging in early cerebral infarction patients has certain diagnostic application value,can evaluate the prognosis of patients,and provide a certain basis for clinical treatment,and further predict patient prognosis based on the final infarct volume.
作者
周晶
ZHOU Jing(Pingxiang People's Hospital,Jiangxi Province,Pingxiang 337000,China)
出处
《中国医学创新》
CAS
2023年第34期161-166,共6页
Medical Innovation of China
关键词
脑灌注CT成像
早期脑梗死
诊断价值
预后评估
Cerebral perfusion CT imaging
Early cerebral infarction
Diagnosis value
Prognostic evaluation
作者简介
通信作者:周晶。
