摘要
目的探究中英心血管疾病(CVD)患者体力活动差异,并比较其影响因素。方法利用中国慢性病前瞻性研究(CKB)项目和英国生物银行(UKB)基线调查数据,根据问卷中自报的疾病史确定病例组和对照组。以代谢当量(MET)作为体力活动水平的衡量指标,并按不同年龄、性别的MET值三分位数进行分级,使用多重logistic回归分析CVD患病与体力活动水平的相关性。结果共纳入509170名中国成年人和360360名英国成年人作为研究对象,多因素调整分析结果显示,CKB和UKB人群CVD患病与低体力活动水平均呈正相关(CKB:OR=1.21,95%CI:1.17~1.25;UKB:OR=1.24,95%CI:1.20~1.28)。CKB中男性CVD患病与低体力活动水平有较高相关性(OR=1.33,95%CI:1.27~1.40)。与UKB人群不同,CKB人群随着CVD患病年限的延长,体力活动水平逐渐恢复并接近非CVD人群,且患有脑卒中与低体力活动水平呈正相关(OR=1.46,95%CI:1.38~1.53)。CKB和UKB人群均表现出低文化程度、当前吸烟或已戒烟、已戒酒、患有其他慢性病与低体力活动水平有较高相关性。CKB中,农村地区人群和非退休人群CVD患病与低体力活动水平之间的相关性较高。UKB中则表现出城市人群和非在职人群CVD患病与低体力活动水平之间的相关性较高。结论中英CVD患者体力活动水平均较低于非CVD人群。除了低文化程度者、当前吸烟或已戒烟者、已戒酒者,以及患有其他慢性病者外,在中国患者中尤其应关注农村、男性、非退休者的体力活动水平。
Objective To explore the differences of physical activity levels between Chinese and British patients with cardiovascular disease(CVD)and its influencing factors.Methods Based on the baseline survey of China Kadoorie Biobank(CKB)and United Kingdom Biobank(UKB),we identified the case and control group according to the self-reported disease history in the questionnaire.Metabolic equivalent of task,as the assessment of physical activity level,was graded according to the tertiles of specific ages and genders.Multiple logistic regression models were used to analyze the correlation between CVD status and physical activity levels.Results We included 509170 Chinese adults and 360360 British adults in the analysis.After adjusting for multiple factors,we found a positive correlation between CVD patients and low physical activity levels in both CKB and UKB populations(CKB:OR=1.21,95%CI:1.17-1.25;UKB:OR=1.24,95%CI:1.20-1.28).There was a high correlation between the prevalence of CVD and low physical activity levels in males with CKB(OR=1.33,95%CI:1.27-1.40).Unlike the UKB population,as the length of CVD increased,the physical activity levels of CKB patients gradually approached that of the non-CVD population,and stroke was positively correlated with low physical activity levels(OR=1.46,95%CI:1.38-1.53).The decline in physical activity was more pronounced among CKB and UKB CVD patients with lower educational levels,current or former smokers or drinkers,and those with other chronic diseases.In CKB,there showed a high correlation between CVD disease and low physical activity levels in rural areas and non-retired populations.In UKB,there appeared a higher correlation between CVD disease and low physical activity levels in urban and non-working populations.Conclusions The physical activity levels of CVD patients in both China and the UK were lower than that in non-CVD population.In addition to low-educated individuals,current or former smokers or drinkers,and those with other chronic diseases,it is critical to pay attention to the physical activity levels of rural,male,and non-retirees among Chinese patients.
作者
柯雅蕾
史洪静
吕筠
陈媛媛
邵子伦
李立明
孙点剑一
余灿清
Ke Yalei;Shi Hongjing;Lyu Jun;Chen Yuanyuan;Shao Zilun;Li Liming;Sun Dianjianyi;Yu Canqing(Department of Epidemiology and Biostatistics,School of Public Health,Peking University,Beijing 100191,China;Peking University Center for Public Health and Epidemic Preparedness&Response,Beijing 100191,China;Key Laboratory of Epidemiology of Major Diseases(Peking University),Ministry of Education,Beijing 100191,China)
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2023年第11期1709-1716,共8页
Chinese Journal of Epidemiology
基金
国家自然科学基金(82192904,82192901,82192900)
国家重点研发计划“精准医学研究”重点专项(2016YFC0900500)
中国香港Kadoorie Charitable基金。
关键词
心血管疾病
体力活动
比较研究
影响因素
Cardiovascular disease
Physical activity
Comparative study
Influencing factors
作者简介
通信作者:余灿清,Email:yucanqing@pku.edu.cn;通信作者:孙点剑一,Email:dsun1@bjmu.edu.cn。
