摘要
目的探讨双歧杆菌三联活菌联合蒙脱石散治疗小儿急性轮状病毒性肠炎的临床效果及对免疫球蛋白水平的影响。方法选取2020年3月至2022年11月滕州市西岗中心卫生院收治的80例急性轮状病毒性肠炎患儿为研究对象,以随机数字表法将其分为对照组与观察组,每组各40例。对照组采用蒙脱石散治疗,观察组在对照组基础上联合双歧杆菌三联活菌治疗。比较两组患儿症状改善时间、免疫球蛋白水平。结果观察组大便次数和形态正常时间、退热时间、止吐时间、腹痛缓解时间均短于对照组(P<0.05)。治疗前,两组免疫球蛋白A(IgA)、免疫球蛋白G(IgG)水平比较,差异无统计学意义(P>0.05);治疗后,两组IgA、IgG水平高于治疗前,且观察组IgA、IgG水平高于对照组(P<0.05)。结论双歧杆菌三联活菌联合蒙脱石散治疗小儿急性轮状病毒性肠炎的临床效果显著,能促进症状恢复,提高免疫球蛋白水平。
Objective To explore the clinical effect of Bifidobacterium Triple Viable Bacteria combined with Montmorillonite Powder in the treatment of acute rotavirus enteritis in children and its influence on the level of immunoglobulin.Methods A total of 80 children with acute rotavirus enteritis in Xigang Central Health Center of Tengzhou City from March 2020 to November 2022 were selected and divided into control group and observation group by the random number table method,with 40 cases in each groups.The control group was treated with Montmorillonite Powder,and the observation group was treated with Bifidobacterium Triple Viable Bacteria on the basis of control group.The time of symptom improvement and the level of immunoglobulin were compared between the two groups.Results The time for the frequency and shape of stool to return to normal,antipyretic time,antiemetic time and abdominal pain relief time in the observation group were earlier than those in the control group(P<0.05).Before treatment,there were no statistically significant differences in the levels of immunoglobulin A(IgA)and immunoglobulin G(IgG)between the two groups(P>0.05).After treatment,the levels of IgA and IgG in the two groups were higher than those before treatment,and the levels of IgA and IgG in the observation group were higher than those in the control group(P<0.05).Conclusion Bifidobacterium Triple Viable Bacteria combined with Montmorillonite Powder treating acute rotavirus enteritis in children has significant clinical effect,which can promote the recovery of symptoms and increase the level of immunoglobulin.
作者
葛和春
GE Hechun(Department of Pediatrics,Xigang Central Health Center of Tengzhou City,Shandong Province,Tengzhou 277519,China)
出处
《妇儿健康导刊》
2023年第21期140-142,共3页
JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE
关键词
双歧杆菌三联活菌
蒙脱石散
小儿急性轮状病毒性肠炎
免疫球蛋白
Bifidobacterium Triple Viable Bacteria
Montmorillonite Powder
Acute rotavirus enteritis in children
Immunoglobulin
作者简介
葛和春(1974-),男,汉族,山东滕州人,副主任医师,研究方向:小儿腹泻。
