摘要
目的观察桑麻杏贝汤结合补益宗气法针刺治疗慢性阻塞性肺疾病(稳定期)临床效果。方法研究纳入上海中医药大学附属岳阳中西医结合医院呼吸内科门诊收治的90例慢性阻塞性肺疾病(稳定期)患者(2019年6月—2021年12月),将其以随机数字表法分为两组(对照组与观察组,各45例),对照组患者实施西医治疗(信必可都保160μg/4.5μg),观察组患者实施西医治疗同时结合桑麻杏贝汤及补益宗气法针刺治疗,数据观察:临床疗效、中医证候总积分及圣乔治呼吸问卷评分(SGRQ)、6 min步行试验距离变化、第1秒用力呼气量(FEV_(1))及FEV_(1)占用力肺活量百分比(FEV_(1)/FVC)等肺功能指标变化、不良反应,随访1年,观察治疗前后各组患者1年慢阻肺急性发作次数。结果观察组治疗总有效率(95.56%,43/45)比对照组(82.22%,37/45)更高(P<0.05);治疗前,两组中医证候总积分与SGRQ评分、6 min步行试验距离、FEV_(1)、FEV_(1)/FVC、1年急性发作次数等指标比较差异无统计学意义(P>0.05),治疗后各组患者中医证候总积分与SGRQ评分、6 min步行实验距离、FEV_(1)、FEV_(1)/FVC、1年急性发作次数等指标均改善,观察组患者治疗后中医证候总积分与SGRQ评分、6 min步行实验距离、FEV_(1)、FEV_(1)/FVC、1年急性发作次数等指标优于对照组(P<0.05);两组未见严重不良反应。结论桑麻杏贝汤结合补益宗气法针刺可提升慢性阻塞性肺疾病(稳定期)临床效果,有助改善患者病情,预防其急性发作,安全可靠。
Objective To observe the clinical effect of Sangma Xingbei Decoction(桑麻杏贝汤)combined with benefiting Zongqi acupuncture on chronic obstructive pulmonary disease(stable stage).Methods A total of 90 patients with chronic obstructive pulmonary disease(COPD)who were admitted to the department of Respiratory Medicine outpatient department of Yueyang Hospital of Integrated Traditional and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine from June 2019 to December 2021 were enrolled.They were divided into two groups(control group and observation group,45 cases in each group)by random number table method.The patients in the control group were treated with Western medicin(Sinbikedubao 160μg/4.5μg),while those in the observation group were treated with Western medicine combined with Sangma Xingbei Decoction and benefiting Zongqi acupuncture.The clinical efficacy,total score of TCM syndrome and St.George respiratory Questionnaire score(SGRQ),changes of 6min walking distance,forced expiratory volume in the first second(FEV1)and percentage of FEV1 in forced vital capacity(FEV1/FVC)and other lung function indicators,adverse reactions and 1-year follow-up of two groups were compared.The acute attack frequency of COPD in each group was observed before and after treatment.Results The total effective rate of the observation group(95.56%,43/45)was higher than that of the control group(82.22%,37/45)(P<0.05);Before treatment,the total score of TCM syndrome and SGRQ score,6 min walking distance,FEV1,FEV1/FVC,the number of acute attacks in 1 year were not significant between the two groups(P>0.05).After treatment,the total score of TCM syndrome,SGRQ score,6 min walking distance,FEV1,FEV1/FVC,and the number of acute attacks in 1 year were improved in each group.And those in the observation group were better than those in the control group(P<0.05).No serious adverse reactions were observed in the two groups.Conclusion Sangma Xingbei Decoction combined with benefiting Zongqi acupuncture can improve the clinical effect of COPD(stable stage),help to improve the patients'condition and prevent its acute attack.It is safe and reliable.
作者
盛家刚
季思勤
王振伟
SHENG Jiagang;JI Siqin;WANG Zhenwei(Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China)
出处
《辽宁中医杂志》
CAS
2023年第9期99-102,共4页
Liaoning Journal of Traditional Chinese Medicine
基金
上海市卫生健康委员会中医药科研项目(2020LP019)
上海市卫生健康委员会治未病技术推广项目
岳阳医院中医肺病专科建设项目(YWC-ZK2020-005)。
关键词
稳定期慢性阻塞性肺疾病
桑麻杏贝汤
补益宗气法针刺
疗效
急性发作次数
stable chronic obstructive pulmonary disease
Sangma Xingbei Decoction(桑麻杏贝汤)
benefiting Zongqi acupuncture
curative effect
number of acute episodes
作者简介
盛家刚(1991-),男,上海人,主治医师,硕士,研究方向:慢性阻塞性肺疾病;通讯作者:王振伟(1980-),男,上海人,主任医师,博士,研究方向:慢性阻塞性肺疾病,E-mail:luckytcm@yahoo.com.cn。
