摘要
近年来,肠道微生态学已经成为众学者的研究热点,肠道微生态平衡影响人体健康,尤其与结直肠癌(colorectal cancer,CRC)关系密切。许多CRC患者在早期并无明显症状,在进入中晚期时才被确诊,因错过早期治疗的机会而导致治疗效果欠佳,目前亟需更新更优的CRC早期诊断方法。基于肠道微生态与CRC的密切关系,肠道微生态已成为CRC新诊断方法的主要选择之一,主要研究方向是肠道中的细菌、病毒及其代谢产物的种类与数量的检测。本文就近年来关于肠道微生态对CRC诊断作用的相关热点问题进行概述,并展望肠道微生态在CRC诊断作用研究的主要方向及预期进展,旨在为通过肠道微生态诊断CRC提供理论依据。
In recent years,intestinal microecology has been a research hotspot to scholars.The balance of intestinal microecology affects human health,especially associates with colorectal cancer(CRC).Many CRC patients have no obvious symptoms in the early stage and are diagnosed when the disease enter the middle and late stage.The treatment effect is poor due to missed early treatment.So there is an urgent need for newer and better diagnosis methods of CRC.Based on its close relationship with CRC,intestinal microecology has become one of the important choices for new diagnostic methods of CRC.The main research direction is the detection of the types and quantities of bacteria,viruses and their metabolites in the intestine.This paper summarizes the hotspot issues related to the role of intestinal microecology in the diagnosis of CRC in recent years,and looks forward to the main direction and expected progress in the research on its role in the diagnosis of CRC,in order to provide a theoretical basis for the diagnosis of CRC through intestinal microecology.
作者
朱媛媛
周红光
ZHU Yuanyuan;ZHOU Hongguang(Nanjing University of Chinese Medicine,Jiangsu Province Traditional Chinese Medicine Cancer Prevention and Treatment Collaborative Innovation Center,Nanjing,Jiangsu 210029,China;不详)
出处
《中国微生态学杂志》
CAS
CSCD
2023年第9期1103-1106,共4页
Chinese Journal of Microecology
基金
国家自然科学基金面上项目(81973737)。
关键词
肠道微生态
肠道菌群
结直肠癌
Intestinal microecology
Intestinal flora
Colorectal cancer
作者简介
朱媛媛(1997-),女,硕士,从事中西医结合治疗肿瘤的研究,E-mail:m18530123686@163.com;通信作者:周红光,E-mail:zhouhongguang2288@163.com。
