摘要
目的 了解云南省普洱地区男性不育症患者泌尿生殖道病原体感染现状,为临床诊治提供依据。方法 选取2019年8月至2021年12月该院生殖遗传中心门诊初次就诊的男性不育症患者800例。采用实时荧光核酸恒温扩增技术检测解脲支原体(UU)、沙眼衣原体(CT)、淋病奈瑟菌(NG)、生殖支原体(MG)4种病原体感染率,并比较不同年龄段患者泌尿生殖道病原体感染情况。结果 800例患者中,泌尿生殖道病原体感染410例(51.2%),其中UU感染387例(48.4%),CT感染30例(3.8%)、MG感染26例(3.3%)、NG感染3例(0.4%)。不同年龄段患者泌尿生殖道病原体总感染率比较,差异有统计学意义(P<0.05),其中22~25岁患者感染率最高(66.2%),其次为>40岁患者(61.5%)。在单一病原体感染中,不同年龄段患者UU、CT感染率比较,差异有统计学意义(P<0.05)。结论 普洱地区男性不育症患者泌尿生殖道病原体感染率较高,临床应高度关注UU感染情况,同时应加强对22~25岁及>40岁男性不育症患者的干预,以提高该地区生殖健康水平。
Objective To understand the current situation of urogenital pathogen infection in male infertility patients in Pu′er area of Yunnan Province,and to provide evidence for clinical diagnosis and treatment.Methods A total of 800 male infertility patients who first visited the outpatient department of the Reproductive Genetics Center of the hospital from August 2019 to December 2021 were selected.The infection rates of Ureaplasma urealyticum(UU),Chlamydia trachomatis(CT),Neisseria gonorrhoeae(NG),and Mycoplasma genitalium(MG)were detected by simultaneous amplification and testing method.The infection status of urogenital pathogens in patients of different age groups was compared.Results Among 800 patients,410 cases(51.2%)were infected by urogenital pathogens,including 387 cases(48.4%)of UU infection,30 cases(3.8%)of CT infection,26 cases(3.3%)of MG infection and 3 cases(0.4%)of NG infection.There was statistically significant difference in the total infection rate of urogenital pathogens among patients of different age groups(P<0.05).Among them,patients aged 22-25 had the highest infection rate(66.2%),followed by patients over 40 years old(61.5%).There were statistically significant differences in the infection rates of UU and CT among patients of different age groups in single pathogen infection(P<0.05).Conclusion The infection rate of urogenital pathogens in male infertility patients in Pu′er area is relatively high,and clinical attention should be paid to the situation of UU infection.At the same time,intervention should be strengthened for male infertility patients aged 22-25 years and over 40 years to improve the reproductive health level in this area.
作者
陈怡颖
杨涵
陈怡蓉
王金凤
苏洪
戴欢欢
乔宇
张亚勤
CHEN Yiying;YANG Han;CHEN Yirong;WANG Jinfeng;SU Hong;DAI Huanhuan;QIAO Yu;ZHANG Yaqin(Department of Ophthalmology,Pu′er People′s Hospital,Pu′er,Yunnan 665000,China;Reproductive Genetics Center,Pu′er People′s Hospital,Pu′er,Yunnan 665000,China;Department of Infection Management,Pu′er People′s Hospital,Pu′er,Yunnan 665000,China)
出处
《现代医药卫生》
2023年第19期3312-3314,3319,共4页
Journal of Modern Medicine & Health
基金
云南省临床医学研究中心开放项目(2020LCZXKF-SZ18)
云南省普洱市人民医院院内科研项目(2020YN03、2020YN17)。
关键词
泌尿生殖道
感染
不育症
支原体
Urogenital tract
Infection
Infertility
Mycoplasma
作者简介
陈怡颖(1988-),硕士研究生,主治医师,主要从事眼科学相关的研究。;通信作者:张亚勤,E-mail:mayizyq@126.com。
