摘要
受生物体内离子通道的启发,科学家们构建了一系列具有相似作用的人工纳米通道。固态纳米通道以离子电流为检测信号,可以为化学传感提供快速、高灵敏度的检测结果。固态纳米通道机械性能好、稳定性高、结构可调节和容易功能化,在化学传感器中引起极大关注。在多种探针的作用下,固态纳米通道传感器对离子、小分子、核酸、蛋白质等多种靶标物质具有特异性识别作用。
Solidstate nanochannels use ionic current as detection signal,which can provide rapid and highly sensitive detection results for chemical sensing.Solidstate nanochannels have attracted great attention in chemical sensors because of their good mechanical properties,high stability,adjustable structure and easy functionalization.Under the action of a variety of probes,the solidstate nanochannel sensor has a specific recognition function for a variety of target substances such as ions,small molecules,nucleic acids,proteins,etc.This review aims to introduce the sensing principle and research progress of solid-state nanochannels in chemical sensors,with emphasis on their applications in the detection of metal ions,DNA and proteins.Finally,the challenges in the future of functional solidstate nanochannel chemical sensors are briefly prospected.
作者
秦易锦
韦良
杨晶
张宏喜
杨显德
QIN Yi-jin;WEI Liang;YANG Jing;ZHANG Hong-xi;YANG Xian-de(Guangxi Key Laboratory of Natural Polymer Chemistry and Physics,Nanning Normal University,Nanning 530100,China)
出处
《南宁师范大学学报（自然科学版）》
2023年第3期69-75,共7页
Journal of Nanning Normal University：Natural Science Edition
基金
广西高校中青年教师科研基础能力提升项目(2021KY0387)。
关键词
固态纳米通道
检测
传感器
solidstate nanochannel
detection
sensor
作者简介
第一作者:秦易锦(2000-),广西玉林人,硕士生,微纳米孔道功能化及其分析检测应用方向;通信作者:杨显德(1986-),广西钦州人,材料科学与工程博士,研究方向:光催化材料的制备及其光催化活性研究,仿生微纳米孔道可控修饰及其应用(yangxdennnu.edu.cn)。
