摘要
BACKGROUND Male breast cancer(MBC)is an extremely rare condition and accounts for less than 1%of all breast cancers,and malignant tumors occur in less than 1%of the affected men.Mucinous breast cancer is extremely rare and accounts for 2%of all invasive breast cancers.Generally,MBC is accompanied by a retroareolar mass.CASE SUMMARY Herein,we report a case of male mucinous breast carcinoma(MMBC)without gynecomastia development and with mass localization outside the common retroareolar region,wherein the mass was a painless nodule in the right breast of a 64-year-old man.We also discuss the clinical and pathological characteristics of this unusual tumor.The excised breast specimen showed pure mucinous carcinoma.The patient had strong expression of estrogen and progesterone receptors,a low Ki-67 proliferation index of the tumor cells,and negative pathological axillary lymph nodes.The patient underwent modified radical mastectomy and axillary lymph node dissection,followed by tamoxifen hormone therapy.CONCLUSION To the best of our knowledge,this is the first case report of MMBC in the nonretroareolar region of the nipple without gynecomastia development.Mucinous tumors are easily missed during diagnosis,and the incidence of axillary lymph node metastases of chest mucinous tumors has increased.
作者简介
Corresponding author:Qiang Sun,PhD,Chief Doctor,Department of Breast Surgery,General Hospital of Benxi Iron&Steel Industry Group of Liaoning Health Industry Group,No.29 Renming Road,Benxi 117000,Liaoning Province,China.sq1338@hotmail.com,ORCID number:0000-0001-5936-8086;Xu-Yan Liu,ORCID number:0000-0002-9892-9752;Qi Zhang,ORCID number:0000-0002-7303-1399;Hai Jiang,ORCID number:0000-0003-4826-8500.
