摘要
肥厚型心肌病是儿童第二常见的心肌病,具有高度异质性,病因机制和临床表现各异,易发展为心源性猝死。目前临床诊断主要依赖超声心动图和磁共振成像,结合临床表现、胸片、心电图及其他特殊检查综合诊断,部分病因诊断可依赖于基因检测。同时,研究人员一直致力于早期评估心源性猝死风险并利用相关指标建立预测模型。现结合相关文献及最新的研究进展对以上方面展开论述。
Hypertrophic cardiomyopathy is the second common cardiomyopathy in children.It is highly heterogeneous,with different etiological mechanisms and clinical manifestations,and is prone to develop into sudden cardiac death.At present,clinical diagnosis methods mainly rely on ultrasonocardiography and magnetic resonance imaging,combined with clinical manifestations,chest radiographs,electrocardiogram and other special examinations for comprehensive diagnosis,and some etiological diagnosis can rely on gene detection.At the same time,researchers have been committed to early assess the risk of sudden cardiac death and use risk related indicators to build a prediction model.This paper discusses the above aspects in combination with relevant literature and the latest research progress.
作者
王蕊
赵鹏军
WANG Rui;ZHAO Pengjun(Shanghai Jiaotong University School of Medicine,Shanghai 200025,China;Pediatric Heart Center,Xinhua Hospital Affiliated to Medical College of Shanghai Jiaotong University,Shanghai 200092,China)
出处
《心血管病学进展》
CAS
2023年第8期681-685,共5页
Advances in Cardiovascular Diseases
基金
上海交通大学医学院2022年儿科学专业“5+3”科研能力提升计划(DKY20220007)。
关键词
儿童
肥厚型心肌病
辅助检查
猝死
风险评估
Children
Hypertrophic cardiomyopathy
Auxiliary examination
Sudden death
Risk assessment
作者简介
通信作者:赵鹏军,E-mail:pjunzhao@sina.com。
