摘要
目的基于“心肺同治”理论观察艾灸心俞和肺俞配合药物治疗气虚血瘀型慢性心力衰竭的临床疗效。方法将60例气虚血瘀型慢性心力衰竭患者随机分为观察组和对照组,每组30例。对照组采用常规西药治疗,观察组在对照组基础上采用艾灸心俞和肺俞治疗。观察两组治疗前后心功能指标[左心室射血分数(left ventricular ejection fraction,LVEF)和心率(heart rate,HR)]及血清炎性因子指标[C反应蛋白(C-reactive protein,CRP)和髓过氧化物酶(myeloperoxidase,MPO)]的变化情况,并比较两组临床疗效及中医证候疗效。结果两组治疗后LVEF较同组治疗前显著上升,HR及MPO、CRP水平显著下降,差异均具有统计学意义(P<0.05)。观察组治疗后各项心功能指标及炎性因子指标与对照组比较,差异均具有统计学意义(P<0.05)。观察组治疗后临床总有效率及中医证候总有效率分别为90.0%和96.7%,明显高于对照组的66.7%和73.3%,差异均具有统计学意义(P<0.05)。结论艾灸配合药物治疗气虚血瘀型慢性心力衰竭疗效确切,能提高患者的心功能,减轻炎症反应。
Objective To observe the clinical efficacy of moxibustion at Xinshu(BL15)and Feishu(BL13)plus medication in treating chronic heart failure(CHF)of blood stasis due to Qi deficiency syndrome based on the theory of“concurrent treatment of heart and lung”.Method Sixty patients with CHF of blood stasis due to Qi deficiency syndrome were randomized into an observation group and a control group,with 30 cases in each group.The control group was intervened by conventional Western medications,and the observation group received moxibustion at Xinshu and Feishu in addition to the intervention in the control group.Before and after the treatment,cardiac function parameters[left ventricular ejection fraction(LVEF)and heart rate(HR)]and serum inflammatory factors[C-reactive protein(CRP)and myeloperoxidase(MPO)]were observed for the two groups.Clinical efficacy and efficacy based on Chinese medicine symptoms were also compared.Result The LVEF increased significantly after the treatment in both groups,and HR and the MPO and CRP levels dropped notably,all presenting statistical significance(P<0.05).After the treatment,there was statistical significance in comparing each cardiac function parameter and inflammatory factor between the two groups(P<0.05).The observation group had a total clinical effective rate of 90.0%and a total effective rate based on Chinese medicine symptoms of 96.7%,markedly higher than 66.7%and 73.3%in the control group,showing statistical significance(P<0.05).Conclusion Moxibustion plus medication can produce evident efficacy in treating CHF of blood stasis due to Qi deficiency syndrome;it can enhance cardiac function and reduce inflammatory reactions.
作者
王祝
夏冉
高兵
朱梦
汪恒
李凌基
王茎
WANG Zhu;XIA Ran;GAO Bin;ZHU Meng;WANG Heng;LI Lingji;WANG Jing(Anhui University of Chinese Medicine,Hefei 230012,China;The First Affiliated Hospital of Anhui University of Chinese Medicine,Hefei 230038,China;Key Laboratory of Xin’an Medicine,Ministry of Education,Anhui University of Chinese Medicine,Hefei 230038,China)
出处
《上海针灸杂志》
CSCD
2023年第8期797-801,共5页
Shanghai Journal of Acupuncture and Moxibustion
基金
国家自然科学基金面上项目(81273856,81574084)
安徽省重点研究与开发计划项目(202004j07020045)
新安医学教育部重点实验室开放基金项目(2020xayx07)
安徽省教育厅重点项目(KJ2021A0570)。
关键词
灸法
艾条灸
心力衰竭
心功能
气虚血瘀
穴
心俞
穴
肺俞
Moxibustion
Moxa stick moxibustion
Heart failure
Cardiac function
Blood stasis due to Qi deficiency
Point,Xinshu(BL15)
Point,Feishu(BL13)
作者简介
王祝(1993-),女,2020级硕士生,Email:hfwangzhu@126.com;通信作者:王茎(1964-),男,教授,Email:wangjing2161@126.com。
