摘要
目的研究麦角新碱联合卡贝缩宫素预防二次剖宫产产后出血的效果。方法选取本院于2020年1月至2022年12月收治的二次剖宫产患者200例,随机分为对照组(100例)和观察组(100例),对照组患者采用卡贝缩宫素预防产后出血,观察组采用麦角新碱+卡贝缩宫素预防产后出血。对比两组治疗效果。结果观察组患者产后2 h、24 h出血量少于对照组,对比结果差异显著(t=11.864、11.570,P<0.05)。观察组患者子宫内膜厚度低于对照组,血红蛋白高于对照组,对比结果差异显著(t=6.183、8.412,P<0.05)。观察组患者手术时间、住院时间短于对照组,对比结果差异显著(t=7.891、5.029,P<0.05)。观察组患者舒张压、收缩压与对照组比较无显著差异(t=0.133、0.206,P>0.05)。观察组患者血管紧张素Ⅰ、血管紧张素Ⅱ、肾素活性低于对照组,对比结果差异显著(t=7.891、5.029、5.029,P<0.05)。观察组患者不良反应总发生率、产后出血率低于对照组,对比结果差异显著(χ^(2)=4.258、5.736,P<0.05)。结论卡贝缩宫素联合麦角新碱预防产后出血的效果明显优于单用卡贝缩宫素。
Objective To study the effect of ergometrine combined with cabetocin on preventing postpartum hemorrhage after secondary cesarean section.Methods A total of 200 patients with second cesarean section admitted to our hospital from January 2020 to December 2022 were selected,including a control group(100 cases)and an observation group(100 cases).The control group received cabetocin for prevention of postpartum hemorrhage during the second cesarean section,while the observation group received ergoxine and cabetocin for prevention of postpartum hemorrhage.Compare the effects of treatment in the two groups.Results The blood output of patients in the observation group at 2 and 24 hours postpartum was less than that of the control group,and the difference in comparison results was significant(t=11.864,11.570,P<0.05).The observation group had lower endometrial thickness and higher hemoglobin levels in patients compared to the control group,with significant differences in comparison results(t=6.183,8.412,P<0.05).The observation group had shorter surgical time and hospital stay for patients undergoing secondary cesarean section compared to the control group,with significant differences in comparison results(t=7.891,5.029,P<0.05).There was no significant difference in diastolic blood pressure and systolic blood pressure between the observation group and the control group after a second cesarean section(t=0.133,0.206,P>0.05).The activity of angiotensin I,angiotensin II,and renin in the observation group with secondary cesarean section was lower than that in the control group,and the difference in comparison results was significant(t=7.891,5.029,5.029,P<0.05).The total incidence of adverse reactions and postpartum bleeding in the observation group was lower than that in the control group,and the difference in comparison results was significant(χ^(2)=4.258,5.736,P<0.05).Conclusion The combination of ergometrine to prevent postpartum hemorrhage has more promotional value.
作者
李涓
LI Juan(Department of Obstetrics,Anxi County Maternal and Child Health Hospital,Anxi 362400,China)
出处
《中国医药指南》
2023年第22期116-118,共3页
Guide of China Medicine
关键词
二次剖宫产
产后出血
麦角新碱
卡贝缩宫素
不良反应
Second cesarean section
Postpartum hemorrhage
Ergoxine
Cabe oxytocin
Adverse reactions
