摘要
目的分析超声参数与肾盂输尿管连接部梗阻(UPJO)致肾积水患儿肾功能的相关性。方法选取徐州市儿童医院2020年2月至2021年4月收治的92例UPJO致肾积水患儿(疾病组)和92例健康体检小儿(对照组)作为研究对象。应用彩色多普勒超声测量肾叶间动脉阻力指数(RI)、收缩期最大血流速度(V_(max))及舒张期最小血流速度(V_(min)),计算动脉阻力指数比率(RIR),采用肾核素动态显像法测定肾小球滤过率(GFR),以及酶法检测血尿素氮(BUN)与血肌酐(SCr)水平。对比疾病组与对照组的超声参数(RI、V_(max)、V_(min)、RIR)和肾功能指标(GFR、BUN、SCr),采用Pearson法分析疾病组超声参数与肾功能指标的相关性。结果疾病组肾脏V_(max)、V_(min)、GFR均低于对照组(P<0.05),RI、RIR、BUN、SCr均高于对照组(P<0.05);疾病组RI、RIR与GFR均呈负相关(P<0.05),与BUN、SCr均呈正相关(P<0.05);疾病组V_(max)、V_(min)与GFR均呈正相关(P<0.05),与BUN、SCr均呈负相关(P<0.05)。结论UPJO致肾积水患儿与健康小儿相比,RI、RIR增大,V_(max)、V_(min)减小,超声参数与肾功能指标有相关性。
Objective To analyze the correlation between ultrasonic parameters and renal function in children with hydronephrosis caused by ureteropelvic junction obstruction(UPJO).Methods 92 children(disease group)with hydronephrosis caused by UPJO treated in Xuzhou Children's Hospital from February 2020 to April 2021 and 92 healthy children(control group)were selected.The renal interlobar artery resistance index(RI),systolic maximum blood flow velocity(V_(max))and diastolic minimum blood flow velocity(V_(min))were measured by color Doppler ultrasound,and the arterial resistance index ratio(RIR)was calculated,glomerular filtration rate(GFR)was measured by renal radionuclide dynamic imaging,and the contents of blood urea nitrogen(BUN)and serum creatinine(SCr)were detected by enzyme method.Ultrasound parameters(RI,V_(max),V_(min),RIR)and renal function indexes(GFR,bun,SCR)were compared between the disease group and control group,and Pearson method was used to analyze the correlation between ultrasound parameters and renal function indexes in the disease group.Results V_(max),V_(min) and GFR of kidney in the disease group were lower than those in the control group(P<0.05),and RI,RIR,BUN and SCr were higher than those in the control group(P<0.05).RI and RIR were negatively correlated with GFR(P<0.05),positively correlated with BUN and SCr(P<0.05).V_(max) and V_(min) were positively correlated with GFR(P<0.05),negatively correlated with BUN and SCr(P<0.05).Conclusions Compared with healthy children,RI,RIR increased,and V_(max),V_(min) decreased in children with hydronephrosis caused by UPJO.The ultrasound parameters are correlated with renal function.
作者
赵静涵
陈玉龙
张琛
Jinghan Zhao;Yulong Chen;Chen Zhang(Xuzhou Children's Hospital,Jiangsu 221000,China)
出处
《中华腔镜泌尿外科杂志（电子版）》
2023年第4期372-376,共5页
Chinese Journal of Endourology(Electronic Edition)
关键词
超声参数
肾盂输尿管连接部梗阻
肾积水
患儿
肾功能
Ultrasonic parameters
Ureteropelvic junction obstruction
Hydronephrosis
Children
Renal function
作者简介
通信作者:赵静涵,Email:teecb93@163.com。
