摘要
应激被认为是导致疾病的一个重要因素,持续的应激会使机体生理系统出现严重紊乱。非稳态负荷作为评估慢性应激下机体多个系统生理失调的综合指标,可以预示一系列健康问题的发生。本文系统、全面地综述了非稳态负荷的相关概念、评估方法以及非稳态负荷对健康的影响,揭示非稳态负荷与健康之间存在着明显相关性。然而,国内外研究中关于非稳态负荷生物标志物的选择和算法尚无统一标准,这仍是未来的研究方向。
Stress is considered to be an important factor leading to diseases.Continuous stress can cause serious disorders in the physiological system of the body.Allostatic load,as a comprehensive index to assess the physiological disorders of multiple systems in the body under chronic stress,can predict a range of health problems.This paper systematically and comprehensively reviews the related concepts and assessment methods of allostatic load and its impact on health,and reveals a significant correlation between allostatic load and health.However,there is no standardized criteria for the selection and algorithm of biomarkers for allostatic load in domestic and foreign studies,which is still a future research direction.
作者
李懿茹
李玉红
LI Yiru;LI Yuhong(School of Nursing,Anhui Medical University,Hefei 230601,China)
出处
《中国全科医学》
北大核心
2023年第32期4051-4056,共6页
Chinese General Practice
基金
安徽省自然科学基金面上项目(2108085MG242)。
作者简介
通信作者:李玉红,教授,E-mail:liyuhong@ahmu.edu.cn。
