摘要
目的研究2型糖尿病患者采用阿卡波糖、格列吡嗪治疗的治疗效果和药理价值。方法选取2022年1—12月于连云港市灌云县人民医院中就诊的2型糖尿病患者120例为研究对象,采用随机数表法分为两组,每组60例。采用格列吡嗪治疗的为格列吡嗪组,采用阿卡波糖治疗的为阿卡波糖组,比较两组血糖水平、治疗效果、不良反应发生率。结果阿卡波糖组的糖化血红蛋白、空腹血糖、餐后2 h血糖优于格列吡嗪组,差异有统计学意义(P<0.05)。阿卡波糖组总有效率为96.67%高于格列吡嗪组的88.33%,差异有统计学意义(χ^(2)=5.689,P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论将阿卡波糖用于2型糖尿病患者治疗中,可更好地稳定血糖,在用药安全性上亦满足了患者需求。
Objective To study the therapeutic effect and pharmacological value of acarbose and glipizide in patients with type 2 diabetes.Methods A total of 120 patients with type 2 diabetes who received medical treatment in Guanyun County People's Hospital of Lianyungang City from January to December 2022 were selected as the research objects and divided into two groups with 60 patients in each group by random number table method.Glipizide group was treated with glipizide group,and acarbose group was treated with acarbose group.Blood glucose level,therapeutic effect and incidence of adverse reactions were compared between the two groups.Results The glycated hemoglobin,fasting blood glucose,and 2-hour postprandial blood glucose of the acarbose group were better than those of glipizide group,and the difference was statistically significant(P<0.05).The total effective rate of the acarbose group was 96.67%,which was higher than 88.33%of the glipizide group,and the difference was statistically significant(χ^(2)=5.689,P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion When acarbose is used in the treatment of type 2 diabetes mellitus,it can better stabilize blood glucose and other related test values,and also meet the needs of patients in terms of drug safety.
作者
朱为国
梁鸣
贾强强
ZHU Weiguo;LIANG Ming;JIA Qiangqiang(Department of Pharmacy,Guanyun County People's Hospital,Lianyungang,Jiangsu Province,222200 China)
出处
《糖尿病新世界》
2023年第10期112-115,共4页
Diabetes New World Magazine
关键词
阿卡波糖
格列吡嗪
2型糖尿病
血糖
效果分析
Acarbose
Glipizide
Type 2 diabetes mellitus
Blood glucose
Effect analysis
作者简介
朱为国(1992-),男,本科,主管药师,研究方向为糖尿病药学。
