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COPD患者再入院影响因素的Meta分析 被引量:1

Meta-analysis of Influencing Factors of Readmission in COPD Patients
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摘要 目的了解慢性阻塞性肺疾病患者再入院的相关因素。方法计算机检索CNKI、万方数据库、维普数据库、SinoMed、PubMed、Cochrane Library、Web of Science、EMbase,检索时限从建库至2022年7月。采用RevMan 5.3软件进行Meta分析。结果共纳入22篇文献,纳入患者包括279602例,包括47项相关的危险因素。有统计学意义的风险因素包括吸烟[OR=1.41,95%CI(1.17~1.70)]、缺乏运动[OR=2.11,95%CI(1.37~3.24)]、既往有慢阻肺急性加重住院史[OR=2.49,95%CI(2.33~2.69)]、住院时间延长[OR=1.08,95%CI(1.03~1.12)]、FEV_(1)%Pred<50%[OR=2.04,95%CI(1.36~3.06)]、血小板分布宽度增加[OR=3.51,95%CI(2.40~5.13)]、红细胞分布宽度增加[OR=2.25,95%CI(1.48~3.42)]、嗜酸性粒细胞≥200/μl[OR=3.47,95%CI(1.94~6.18)]、查尔森合并症指数增高[OR=1.43,95%CI(1.19~1.72)]、合并糖尿病[OR=9.19,95%CI(2.98~28.32)]。结论吸烟、缺乏运动、既往有慢阻肺急性加重住院史、住院时间延长、FEV_(1)%Pred<50%、血小板分布宽度增加、红细胞分布宽度增加、嗜酸性粒细胞≥200/μl、查尔森合并症指数增高、合并糖尿病是慢性阻塞性肺疾病患者再入院的相关危险因素。 Objective To understand the related factors of readmission in patients with chronic obstructive pulmonary disease.Methods CNKI,Wanfang database,VIP database,SinoMed,PubMed,Cochrane Library,Web of Science,EMbase were searched from inception to July 2022.Meta-analysis was performed using RevMan 5.3 software.Results A total of 22 articles were included,including 279602 patients,with 47 related risk factors.The statistically significant risk factors included smoking[OR=1.41,95%CI(1.17-1.70)],lack of exercise[OR=2.11,95%CI(1.37-3.24)],previous hospitalization history of acute exacerbation of COPD[OR=2.49,95%CI(2.33-2.69)],prolonged hospitalization time[OR=1.08,95%CI(1.03-1.12)],FEV_(1)%Pred<50%[OR=2.04,95%CI(1.36-3.06)],increased platelet distribution width[OR=3.51,95%CI(2.40-5.13)],increased red blood cell distribution width[OR=2.25,95%CI(1.48-3.42)],eosinophils≥200/μl[OR=3.47,95%CI(1.94-6.18)],increased Charlson comorbidity index[OR=1.43,95%CI(1.19-1.72)]and diabetes[OR=9.19,95%CI(2.98-28.32)].Conclusion Smoking,lack of exercise,previous hospitalization history of acute exacerbation of COPD,prolonged hospitalization time,FEV_(1)%Pred<50%,increased platelet distribution width,increased red blood cell distribution width,eosinophil≥200/μl,increased Charlson comorbidity index and diabetes mellitus are risk factors for readmission in patients with chronic obstructive pulmonary disease.
作者 李雄波 吴红霞 张西洋 郭晋荣 刘顺芳 LI Xiong-bo;WU Hong-xia;ZHANG Xi-yang;GUO Jin-rong;LIU Shun-fang(School of Nursing,Shanxi University of Chinese Medicine,Taiyuan 030000,Shanxi,China;Department of Respiratory and Critical Care Medicine,Shanxi Provincial People's Hospital,Taiyuan 030000,Shanxi,China)
出处 《医学信息》 2023年第13期31-37,共7页 Journal of Medical Information
基金 2019山西省软科学研究一般项目(编号:2019041041-3)。
关键词 慢性阻塞性肺疾病 再入院 危险因素 Chronic obstructive pulmonary disease Readmission Risk factors
作者简介 李雄波(1996.11-),男,山西运城人,硕士研究生,主要从事老年护理研究;通讯作者:吴红霞(1966.11-),女,山西太原人,本科,主任护师,主要从事临床护理管理和教育研究。
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