摘要
目的探讨糖尿病足采用前列地尔注射液治疗的临床效果。方法选取2021年1月至2022年1月北京丰台医院内分泌科收治的80例糖尿病足患者作为研究对象,按照接诊的先后次序分为常规组(40例)与综合组(40例)。常规组采用常规综合治疗,综合组采用常规综合治疗+前列地尔注射液。比较两组的治疗效果、足背动脉血流动力学指标及生活质量相关指标。结果综合组的治疗总有效率高于常规组,差异有统计学意义(P<0.05);综合组治疗后的血管内径、血流流速、搏动指数高于常规组,阻力指数低于常规组,差异有统计学意义(P<0.05);综合组治疗后的各项生活质量评分高于常规组,差异有统计学意义(P<0.05)。结论糖尿病足患者采用前列地尔注射液治疗后,能改善足部末梢循环,促进创面愈合,提高生活质量,值得临床采纳。
Objective To explore the clinical effect of Alprostadil Injection on diabetes foot.Methods A total of 80 patients with diabetes foot who were admitted to the Department of Endocrinology in Beijing Fengtai Hospital were selected as the study subjects from January 2021 to January 2022,they were divided into the routine group(40 cases)and the comprehensive group(40 cases)according to the order of reception.The routine group was treated with routine comprehensive treatment,while the comprehensive group was treated with routine comprehensive treatment+Alprostadil Injection.The therapeutic effect,hemodynamic indexes of dorsalis pedis artery and quality of life related indexes were compared between the two groups.Results The total effective rate of treatment in the comprehensive group was higher than that in the routine group,the difference was statistically significant(P<0.05).After treatment,the vascular diameter,blood flow velocity,and pulsatile index of the comprehensive group were higher than those of the routine group,while the resistance index was lower than that of the routine group,the differences were statistically significant(P<0.05).After treatment,the scores of various quality of life in the comprehensive group were higher than those in the routine group,the differences were statistically significant(P<0.05).Conclusion After treatment with Alprostadil Injection,patients with diabetes foot can not only improve foot peripheral circulation,but also promote wound healing and improve their quality of life,which is worthy of clinical adoption.
作者
徐宏燕
XU Hongyan(Department of Endocrinology,Beijing Fengtai Hospital,Beijing 100070,China)
出处
《中国当代医药》
CAS
2023年第17期65-68,共4页
China Modern Medicine
