摘要
目的 探讨冷冻切片和细胞学涂片在卵巢肿瘤病理诊断中的应用价值。方法 选择2019年1月至2022年12月在睢县中医院接受治疗的94例卵巢肿瘤患者的数据进行回顾性分析。描述全部纳入研究患者的一般情况,石蜡切片的诊断结果分布情况。以石蜡切片的诊断结果作为金标准,分析细胞涂片检查和冷冻切片检查的诊断结果。分析细胞涂片检查、冷冻切片检查以及两种方法联合诊断的效率。结果 患者平均年龄(53.89±10.67)岁。卵巢肿瘤平均病程(7.36±2.61)个月。石蜡切片的诊断结果显示,存在良性病变38例(40.43%),存在恶性病变56例(59.57%)。其中卵巢上皮间质瘤65例(69.15%),性索-间质瘤21例(22.34%),生殖细胞瘤4例(4.26%),转移癌4例(4.26%)。细胞涂片检查、冷冻切片检查以及两种方法联合诊断的灵敏度、准确度、阴性预测值数据差异有统计学意义(P <0.05)。其中联合诊断的灵敏度、准确度、阴性预测值高于单项诊断差异有统计学意义(P <0.05),且联合诊断同石蜡切片诊断的Kappa值也高于单项诊断。细胞涂片检查、冷冻切片检查以及两种方法联合诊断的特异度、阳性预测值数据差异无统计学意义(P> 0.05)。结论 在卵巢肿瘤的手术过程中,采取冷冻切片检查和细胞学涂片检查均可以获得良好的病理诊断结果,如果将两种方法联合使用,更有利于提升诊断的效率。
Objective To explore the application value of frozen sections and cytological smears in the pathological diagnosis of ovarian tumors.Methods The data of 94 patients with ovarian tumors who were treated in Suixian Traditional Chinese Medicine Hospital from January 2019 to December 2022 were retrospectively analyzed.Describe the general situation of all patients included in the study.Distribution of diagnostic results on paraffin sections.Using the diagnostic results of paraffin sections as the gold standard,the diagnostic results of cell smears and frozen sections were analyzed.Analyze the efficiency of cell smear examination,frozen section examination,and combined diagnosis of the two methods.Results The average age of the patient is(53.89±10.67)years old.The average course of ovarian tumors is(7.36±2.61)months.The diagnostic results of paraffin sections showed that 38 cases(40.43%)had benign lesions and 56 cases(59.57%)had malignant lesions.Among them,65 cases(69.15%)were epithelial stromal tumors of the ovary,21 cases(22.34%)were sex cord stromal tumors,4 cases(4.26%)were germ cell tumors,and 4 cases(4.26%)were metastatic carcinomas.The sensitivity,accuracy,and negative predictive value data of cell smear examination,frozen section examination,and the combination of the two methods showed statistically significant differences(P<0.05).The sensitivity,accuracy,and negative predictive value of joint diagnosis were higher than those of single diagnosis,the difference is statistically significant(P<0.05),and the Kappa value of joint diagnosis and paraffin section diagnosis was also higher than that of single diagnosis.There was no statistically significant difference in the specificity and positive predictive value of cell smear examination,frozen section examination,and the combination of the two methods for diagnosis(P>0.05).Conclusion During the surgical procedure for ovarian tumors,both frozen section examination and cytological smear examination can obtain good pathological diagnosis results,but if the two methods are combined,it is more beneficial to improve the diagnostic efficiency.
作者
刘粉荣
LIU Fenrong(Department of Pathology,SuiXian Traditional Chinese Medicine Hospital,Shangqiu Henan 476900,China)
出处
《临床研究》
2023年第6期115-117,共3页
Clinical Research
关键词
冷冻切片
细胞学涂片
卵巢肿瘤
病理诊断
生殖系统
frozen section
cytological smear
ovarian tumors
pathological diagnosis
reproductive system
作者简介
刘粉荣,女,主治医师,本科。研究方向:临床病理学。
