摘要
Helicobacter pylori(H.pylori)infection is widely prevalent worldwide.H.pylori infection has been reported to be a risk factor for the development of insulin resistance,nonalco-holic fatty liver disease(NAFLD),nonalcoholic steatohepatitis(NASH),liver fibrosis,and cirrhosis.Because treatment for NAFLD,other than weight loss is limited,the treatment for H.pylori infection is well established.It is important to determine whether screening and treatment for H.pylori infection should be considered in patients with no gastrointestinal symptoms.The aim of this mini-review is to evaluate the association be-tween H.pylori infection and NAFLD including epidemiology,pathogenesis,and the evidence for H.pylori infection as a modifiable risk factor for preventing or treating NAFLD.
作者简介
George Y.Wu(Comprehensive Editor-in-Chief)Prof.Wu obtained his MD and PhD degree at Albert Einstein College of Medicine in 1976.He was a resident at Harlem Hospital Center from 1976 to 1979.He worked as a post-doctoral fellow at Albert Ein-stein College of Medicine from 1979 to 1982.From 1983,he worked as Assistant Professor and then Professor at University of Connecticut School of Medicine.He is now the Director of Hepatology Section,Division of Gastro-enterology-Hepatology.Dr.Wu’s awards include the following:Research Prize awarded by the American Liver Foundation in 1982,Industry Research Scholar Award from the American Gastroenterological Association for 1985 to 1988,Gastroenterology Research Group Young Scientist Award from the American Gastroenterologi-cal Association in 1990,Herman Lopata Chair in Hepatitis Research from 1992 to date,Scientific Award from the Chinese American Medical Society in 1992,He was elected to membership in exclusive societies:American Society for Clinical Investigation in 1989,Association of American Physicians in 1995,and Top Doctor in the U.S.awarded by U.S.News and World Report in 2011.He has published about 180 peerreviewed academic articles,11 books,and is series editor for Clinical Gastroenterology book series by Springer-Nature,and is Senior Associate editor of J.Digestive Diseases;Correspondence to:Murali Dharan,Department of Medicine,Division of Gastroenterology and Hepatology,University of Connecticut Health Center,263 Farmington Avenue,Farmington CT 06030,USA.ORCID:https://orcid.org/0000-0002-9764-0068.Tel:+1-860-679-4124,Fax:+1-860-679-3159,E-mail:dharan@uchc.edu。
