摘要
目的建立甘肃地区42 d至6岁儿童末梢血血常规参数参考区间。方法对19361例42 d至6岁体检合格儿童末梢血进行血常规检测,依据性别和年龄对研究对象进行分组,根据卫生行业标准WS/T 402-2012的方法对各项参数进行统计学分析,得出各项参数的参考区间。结果在42 d至6岁儿童中,血红蛋白水平在2岁后趋于稳定,在>2~6岁儿童中不同性别间差异有统计学意义(P=0.0128);42 d至6岁儿童血小板计数(PLT)随年龄增加而减少,女童PLT略高于男童,且在42 d至2岁儿童中不同性别间差异有统计学意义(P<0.01);单核细胞百分比、嗜酸性粒细胞百分比、嗜碱性粒细胞百分比、单核细胞绝对值、嗜酸性粒细胞绝对值及嗜碱性粒细胞绝对值在同年龄段不同性别间差异均有统计学意义(P<0.05);淋巴细胞百分比在>3~6岁儿童中不同性别间差异有统计学意义(P<0.05);中性粒细胞百分比及中性粒细胞绝对值在42 d至2岁儿童中不同性别间差异有统计学意义(P<0.05);在>4~6岁时,淋巴细胞绝对值与中性粒细胞百分比趋于相等;嗜酸性粒细胞百分比随年龄的增加而逐渐降低,>3~6岁趋于稳定。结论该研究初步建立了甘肃地区42 d至6岁儿童末梢血血常规参数参考区间。
Objective To establish the reference interval of peripheral blood routine parameters for children aged 42 days to 6 years in Gansu.Methods Peripheral blood routine test was performed on 19361 qualified children aged 42 days to 6 years,and the subjects were grouped according to gender and age.According to the method of health industry standard WS/T 402-2012,statistical analysis was conducted on various parameters,and the reference interval of each parameter was obtained.Results Among the children aged 42 days to 6 years,the hemoglobin concentration tended to be stable after the age of 2 years,and the gender difference was statistically significant in the children aged>2-6 years old(P=0.0128).The platelet count(PLT)of children aged 42 days to 6 years decreased with age increasing,the PLT of girls was slightly higher than that of boys,and there was a statistically significant difference between different genders in children aged 42 days to 2 years(P<0.01).There were significant differences in monocyte percentage,eosinophil percentage,basophil percentage,monocyte absolute value,eosinophil absolute value and basophil absolute value between different genders at the same age(P<0.05).The lymphocyte percentage in children>3-6 years old was significantly different between genders(P<0.05).The neutrophil percentage and neutrophil absolute value in children aged 42 days to 2 years were significantly different between the genders(P<0.05).The lymphocyte percentage and neutrophil percentage tended to be equal at the age of>4-6 years.The eosinophil absolute value decreased gradually with increasing age and stabilized at the age of>3-6 years.Conclusion This study preliminarily established the reference interval of peripheral blood routine parameters for children aged 42 days to 6 years in Gansu.
作者
韩璐
赵慧敏
石云深
王平平
张颖
钱柏友
汪梦棋
王临艳
HAN Lu;ZHAO Huimin;SHI Yunshen;WANG Pingping;ZHANG Ying;QIAN Baiyou;WANG Mengqi;WANG Linyan(Department of Clinical Laboratory,Chengdu Public Health Clinical Medical Center,Chengdu,Sichuan 610066,China;Department of Clinical Laboratory,Gansu Provincial Maternal and Child Health Care Hospital,Lanzhou,Gansu 730050,China.)
出处
《国际检验医学杂志》
CAS
2023年第9期1025-1030,1034,共7页
International Journal of Laboratory Medicine
基金
甘肃省科技计划项目(20JR10RA424)。
关键词
参考区间
血常规
末梢血
儿童
reference interval
blood routine test
peripheral blood
children
作者简介
韩璐,女,主管技师,主要从事血液基础、血细胞分析方面研究。;通信作者:王临艳,E-mail:wlyan1974@163.com。
