摘要
目的基于CiteSpace对类风湿关节炎与肠道菌群相关文献进行可视化分析。方法检索Web of Science核心合集数据库,选取自建库至2022年8月收录的类风湿关节炎领域内肠道菌群相关的文献,运用CiteSpace 6.1.R2软件对文献的年发文量、作者、国家、机构、关键词进行可视化分析。结果本研究共纳入822篇文献,发文量及被引频次呈增长的趋势,研究学者以LIU Y、LI X、SCHER J为代表,研究机构中纽约大学发文最多,发文量前三位的国家分别是美国、中国和意大利。研究热点主要集中在肠道黏膜免疫、炎症性肠病、分子作用机制、益生菌制剂等方面。结论类风湿关节炎与肠道菌群领域发文量逐年上升,研究热点多,覆盖面积广,但各机构间研究方向相对独立,合作较少;16sRNA测序、益生菌治疗和调节性T细胞机制的探索是该领域未来的研究趋势。
Objective To visual analysis the literature related to rheumatoid arthritis and intestinal flora based on CiteSpace.Methods The Web of Science core collection database was searched,and the literature related to enteric flora in the field of rheumatoid arthritis included since the establishment of the database to August 2022 was selected,and the CiteSpace 6.1.R2 software was used to visual analysis the annual number of articles,authors,countries,institutions,and keywords of the literature.Results A total of 822 papers were included in this study,and the number of publications,and citation frequency showed an increasing trend.Research scholars were represented by LIU Y,LI X,and SCHER J.Among the research institutions,New York University published the most papers,and the top three countries in terms of publications were the United States,China,and Italy.Research hotspots were mainly focused on intestinal mucosal immunity,inflammatory bowel disease,the molecular mechanism of action,and probiotic agents.Conclusion The number of publications in the field of rheumatoid arthritis and intestinal flora is increasing year by year,with many research hotspots and a wide coverage area,but the research directions are relatively independent among institutions,and there is less cooperation;16sRNA sequencing,probiotic therapy,and exploration of regulatory T cell mechanisms are the future research trends in this field.
作者
张馨文
张子旋
安逸
赵鑫
曹炜
ZHANG Xinwen;ZHANG Zixuan;AN Yi;ZHAO Xin;CAO Wei(School of Clinical Medicine,Beijing University of Chinese Medicine,Beijing100029,China;Guang’anmen Hospital,Chinese Academy of Traditional Chinese Medicine,Beijing100053,China;Wangjing Hospital,Chinese Academy of Traditional Chinese Medicine,Beijing100102,China)
出处
《中国医药导报》
CAS
2023年第10期32-36,49,共6页
China Medical Herald
基金
北京市自然科学基金资助项目(7202173)。
作者简介
张馨文(1997.7-),女,北京中医药大学临床医学院2020级中医内科学在读硕士研究生,研究方向:中医药防治风湿免疫病;通讯作者:曹炜(1969.12-),女,博士,教授,研究方向:中医药防治风湿免疫病。
