摘要
目的探讨超声评分法联合血浆人胎盘催乳素(hPL)水平对前置胎盘合并胎盘植入的诊断价值。方法选取2019年9月至2021年10月河北省衡水市第二人民医院收治的128例前置胎盘患者为研究对象。依据病理结果将其分为植入组和未植入组。比较两组患者的临床资料、超声评分、血浆hPL mRNA水平。绘制受试者操作特征曲线以曲线下面积(AUC)评价超声评分法、血浆hPL mRNA水平及两者联合检测对前置胎盘合并胎盘植入的诊断效能。结果128例前置胎盘患者合并胎盘植入68例。植入组超声评分、血浆hPL mRNA水平高于未植入组(P<0.05)。植入组胎盘组织厚度≥3 cm占比、胎盘后低回声带缺失占比、子宫肌层最薄处厚度<1 mm占比、膀胱面粗糙占比、胎盘基底部血流增多占比、宫颈及周边有血流信号占比高于未植入组(P<0.05)。超声评分、血浆hPL mRNA水平为前置胎盘患者胎盘植入发生的影响因素(OR>1,P<0.05)。超声评分法联合血浆hPL mRNA诊断前置胎盘合并胎盘植入的AUC高于超声评分法、血浆hPL单独检测(P<0.05)。结论超声评分法联合血浆hPL mRNA水平对前置胎盘合并胎盘植入的诊断效能较高。
Objective To investigate the diagnostic value of ultrasound scoring method combined with plasma human placental prolactin(hPL)level for placenta previa combined with placenta accreta.Methods A total of 128 patients with placenta previa who were admitted to the Second People’s Hospital of Hengshui,Hebei Province from September 2019 to October 2021 were selected as the research subjects.According to the pathological results,they were divided into implanted group and non-implanted group.The clinical data,ultrasound scores,and plasma hPL mRNA levels of patients were compared between implanted group and non-implanted group.Receiver operating characteristic curve was drawn to evaluate the diagnostic performance of ultrasound scoring method,plasma hPL mRNA level and their combination detected in the diagnosis of placenta previa combined with placenta accreta by area under the curve(AUC).Results There were 68 cases of placenta previa combined with placenta implantation in 128 cases.The ultrasonic score,plasma hPL mRNA level of implanted group was higher than that of non-implanted group(P<0.05).The proportion of placental tissue thickness≥3 cm,the proportion of postplacental hypogyrus vocal cord deletion,the proportion of the thinnest myometrium thickness<1 mm,the proportion of rough bladder surface,the proportion of increased blood flow at the base of the placenta,and the proportion of blood flow signal in cervix and surrounding of implantation group were higher than those in non-implanted group(P<0.05).Ultrasound score method and plasma hPL mRNA level were the influencing factors of patients with placenta accreta combined with placenta previa(OR>1,P<0.05).The AUC of ultrasound scoring method combined with plasma hPL mRNA level in the diagnosis of placenta previa combined with placenta accreta was higher than that of ultrasound scoring method and plasma hPL mRNA level alone(P<0.05).Conclusion Ultrasound scoring method combined with plasma hPL mRNA level have high diagnostic performance for placenta previa combined with placenta accreta.
作者
时明芳
常书娟
张聪祎
SHI Mingfang;CHANG Shujuan;ZHANG Congyi(Department of Ultrasound,the Second People’s Hospital of Hengshui,Hebei Province,Hengshui053000,China)
出处
《中国医药导报》
CAS
2023年第9期97-100,共4页
China Medical Herald
基金
河北省科技计划项目(17277705D)。
关键词
超声评分
人胎盘催乳素
前置胎盘
胎盘植入
诊断
Ultrasound scoring
Human placental prolactin
Placenta previa
Placenta accreta
Diagnosis
