摘要
目的:分析血清中性粒细胞/淋巴细胞比值(NLR)、淋巴细胞/单核细胞比值(LMR)、降钙素原(PCT)水平与肾结石患者经皮肾镜取石术后发生全身炎症反应综合征(SIRS)的相关性。方法:选取2019年11月至2021年11月万载县人民医院收治的62例肾结石患者为研究对象,设为观察组。另选取同期万载县人民医院40名健康体检者,设为对照组。比较两组血清NLR、LMR、PCT水平。依据经皮肾镜取石术后是否发生SIRS将观察组分为SIRS组、非SIRS组,比较SIRS组与非SIRS组血清NLR、LMR、PCT水平,采用Pearson相关性分析血清NLR、LMR、PCT水平与肾结石患者经皮肾镜取石术后发生SIRS的相关性。结果:观察组血清NLR、PCT水平均高于对照组,LMR水平低于对照组,差异有统计学意义(P<0.05);SIRS组血清NLR、PCT水平均高于非SIRS组,LMR水平低于非SIRS组,差异有统计学意义(P<0.05);Pearson相关性分析结果显示,血清NLR、PCT水平与肾结石患者经皮肾镜取石术后发生SIRS均呈正相关,LMR水平与肾结石患者经皮肾镜取石术后发生SIRS呈负相关(P<0.05)。结论:肾结石患者血清NLR、PCT水平升高,LMR水平降低,且血清NLR、PCT水平与经皮肾镜取石术后发生SIRS均呈正相关,LMR水平与经皮肾镜取石术后发生SIRS呈负相关。
Objective: To analyze correlations among serum neutrophil/lymphocyte ratio(NLR), lymphocyte/monocyte ratio(LMR),procalcitonin(PCT) levels and systemic inflammatory response syndrome(SIRS) after percutaneous nephrolithotomy in patients with renal calculi.Methods: 62 patients with renal calculi admitted to Wanzai County People’s Hospital from November 2019 to November 2021 were selected as the study subjects and set as observation group. Another 40 healthy subjects for healthy examination from Wanzai County People’s hospital were selected as control group. The levels of serum NLR, LMR and PCT were compared between the two groups. According to whether SIRS occurred after percutaneous nephrolithotomy, the observation group was divided into SIRS group and non-SIRS group. The levels of serum NLR, LMR and PCT in SIRS group and non-SIRS group were compared. Pearson correlation analysis was used to analyze the correlations among the serum NLR, LMR, PCT levels and SIRS after percutaneous nephrolithotomy. Results: The levels of serum NLR and PCT in the observation group were higher than those in the control group, the level of LMR was lower than that in the control group, and the differences were statistically significant(P<0.05). The levels of serum NLR and PCT in the SIRS group were higher than those in the non-SIRS group, the level of LMR was lower than that in the non-SIRS group,and the differences were statistically significant(P<0.05). Pearson correlation analysis showed that the serum NLR and PCT levels were positively correlated with SIRS after percutaneous nephrolithotomy, and the LMR level was negatively correlated with SIRS after percutaneous nephrolithotomy(P<0.05). Conclusions: The levels of serum NLR and PCT in the patients with renal calculi increase, and the level of LMR decreases. The serum NLR and PCT levels are positively correlated with SIRS after percutaneous nephrolithotomy, and the LMR level is negatively correlated with SIRS.
作者
金桂根
郭基辉
吴琼
范小琴
JIN Guigen;GUO Jihui;WU Qiong;FAN Xiaoqin(Second Ward of First Department of Surgery of Wanzai County People’s Hospital,Yichun 336100 Jiangxi,China;Efeng Township Hospital of Traditional Chinese Medicine,Yichun 336100 Jiangxi,China)
出处
《中国民康医学》
2023年第4期164-166,共3页
Medical Journal of Chinese People’s Health
作者简介
金桂根(1987.01-),男,汉族,江西万载人,本科,主治医师,研究方向为泌尿外科。
