摘要
目的观察峰值应变离散度(PSD)评估^(131)I治疗前出现急性甲状腺功能减退(甲减)的分化型甲状腺癌(DTC)患者左心室功能和收缩同步性的价值。方法纳入52例DTC^(131)I治疗前急性甲减患者为甲减组,以55名健康志愿者为对照组;获取常规超声心动图参数,应用二维斑点追踪成像技术获取左心室整体纵向应变(GLS)和峰值应变离散度(PSD),基底段、中间段和心尖段纵向收缩峰值应变(LPS)和纵向峰值应变达峰时间(TTPLS),比较组间超声参数差异。结果甲减组室间隔舒张末期厚度、左心室后壁舒张末期厚度、左心室相对室壁厚度、PSD、基底段、中间段和心尖段TTPLS均大于,而E峰、e'、GLS、基底段、中间段及心尖段LPS均低于对照组(P均<0.05)。结论PSD可早期定量、准确评估^(131)I治疗前急性甲减DTC患者左心室功能和收缩同步性。
Objective To explore the value of peak strain dispersion(PSD)for evaluating left ventricular function and systolic synchronicity in differentiated thyroid cancer(DTC)patients with acute hypothyroidism before^(131)I treatment.Methods A total of 52 DTC patients with acute hypothyroidism before^(131)I treatment were enrolled(hypothyroidism group),while 55 healthy volunteers were recruited as control group.Parameters of conventional echocardiography were obtained,and global longitudinal strain(GLS),peak strain dispersion(PSD),longitudinal peak strain(LPS)in basal,middle and apical segments and time to peak longitudinal strain(TTPLS)in basal,middle and apical segments were acquired on two-dimensional speckle tracking imaging,and the ultrasonic parameters were compared between groups.Results Interventricular septal thickness at end-diastole,left ventricular posterior wall thickness at end-diastole,relative wall thickness,PSD and TTPLS in basal,middle and apical segments in hypothyroidism group were higher,while E peak,e',GLS and LPS in basal,middle and apical segments were lower than those in control group(all P<0.05).Conclusion PSD could be used for early quantitative and accurate assessment of left ventricular function and systolic synchronicity in DTC patients with acute hypothyroidism before^(131)I treatment.
作者
彭熠
尹立雪
冯洁
张莉
任梅
PENG Yi;YIN Lixue;FENG Jie;ZHANG Li;REN Mei(School of Medical Imaging,North Sichuan Medical College,Nanchong 637000,China;Institute of Ultrasound in Medicine,Sichuan Provincial People's Hospital,the Affiliated Hospital of University of Electronic Science and Technology,Key Laboratory of Ultrasound in Cardiac Electrophysiology and Biomechanics of Sichuan Province,Chengdu 610072,China;Clinical Medicine Academy,Southwest Medical University,Luzhou 646000,China)
出处
《中国医学影像技术》
CSCD
北大核心
2023年第3期346-350,共5页
Chinese Journal of Medical Imaging Technology
基金
国家重点研发计划项目(2020YFC2008000)
国家自然科学基金项目(81671852)
中央高校基本科研业务基金(ZYGX2020ZB038)。
作者简介
第一作者:彭熠(1992-),女,四川眉山人,在读硕士,医师。研究方向:超声医学。E-mail:yiopeng@163.com;通信作者:尹立雪,川北医学院医学影像学院,637000、电子科技大学附属医院·四川省人民医院超声医学研究所超声心脏电生理学与生物力学四川省重点实验室,610072。E-mail:yinlixue_cardiac@163.com。
