摘要
The metabolic syndrome as a consequence of the obesity pandemic resulted in a substantial increase in the prevalence of metabolic-associated fatty live disease(MAFLD)and type 2 diabetes mellitus(T2DM).Because of the similarity in pathobiology shared between T2DM and MAFLD,both disorders coexist in many patients and may potentiate the disease-related outcomes with rapid progression and increased complications of the individual diseases.In fact,awareness about this coexistence and the risk of complications are often overlooked by both hepatologists and diabetologists.Management of these individual disorders in a patient should be addressed wholistically using an appropriate multidisciplinary team approach involving both the specialists and,when necessary,liaising with dieticians and surgeons.This comprehensive review is to compile the current evidence from a diabetologist's perspective on MAFLD and T2DM and to suggest optimal management strategies.
作者简介
Corresponding author:Joseph M Pappachan,FRCP,MD,Professor,Senior Editor,Senior Researcher,Department of Endocrinology and Metabolism,Lancashire Teaching Hospitals NHS Trust,Sharoe Green Lane,Preston PR29HT,United Kingdom.drpappachan@yahoo.co.in,ORCID number:0000-0003-0886-5255;Mohammad Sadiq Jeeyavudeen,ORCID number:0000-0002-1461-0534;Sherouk Fouda,ORCID number:0000-0001-8227-4571。
