摘要
多孔碳酸钙微球是一种良好的新型缓释载体,在药物缓释、农药控释、涂层防护、橡胶抗老化等领域有广阔的应用前景,合成具有丰富纳米孔道的碳酸钙微球是实现缓释的关键。以氯化钙和碳酸钠为反应原料,选用聚丙烯酸(PAA)为表面活性剂、聚苯乙烯磺酸钠(PSS)为晶型调控剂,通过复分解法制备出球霰石型多孔碳酸钙微球。采用扫描电子显微镜、透射电子显微镜、红外光谱仪、粒度分析仪、比表面及孔隙度分析仪、热重分析仪等手段对获得产物进行表征分析,并研究PAA、PSS浓度对碳酸钙微球形貌和晶型的影响。结果表明,在反应温度为80℃、搅拌速率为600 r/min、PAA和PSS的质量浓度分别为3.0 g/L和3.6 g/L时,可制备出粒径均一、形貌良好、孔隙率较大的多孔碳酸钙微球。
Porous calcium carbonate microspheres are good new sustained-release carriers,which have broad application prospects in the fields of drug sustained-release,pesticide controlled release,coating protection,rubber anti-aging and so on.The synthesis of calcium carbonate microspheres with rich nanopores is the key to realize sustained-release.Calcium chloride and sodium carbonate as reaction materials,polyacrylic acid(PAA)as surfactant and polystyrene sodium sulfonate(PSS)as crystal regulator were applied to synthetize spherical calcium carbonate microspheres by double decomposition method.The products were characterized by scanning electron microscopy,transmission electron microscopy,infrared spectroscopy,particle size analysis,specific surface and porosity analysis,and thermogravimetric analysis.The effects of PAA and PSS concentration on the morphology and crystal shape of calcium carbonate microspheres were studied.The results showed that when the reaction temperature was 80℃and the stirring rate was 600 r/min,the concentration of PAA and PSS were 3.0 g/L and 3.6 g/L,respectively,the porous calcium carbonate microspheres possessed uniform particle size.good morphology and large porosity.
作者
邓伟林
黄文柯
黄崇秋
曾杏彬
DENG Weilin;HUANG Wenke;HUANG Chongqiu;ZENG Xingbin(Guangzhou University,Guangzhou 510000,China)
出处
《无机盐工业》
CAS
CSCD
北大核心
2023年第2期67-72,共6页
Inorganic Chemicals Industry
基金
广州大学研究生创新研究资助计划(2021GDJC-M40)。
关键词
聚丙烯酸
聚苯乙烯磺酸钠
多孔碳酸钙微球
调控
polyacrylic acid
sodium polystyrene sulfonate
porous calcium carbonate microspheres
regulation
作者简介
邓伟林(1997-),男,硕士研究生,主要研究方向为多孔材料制备及工艺研究,E-mail:2112016102@e.gzhu.edu.cn;通讯作者:黄文柯(1986-),男,博士,讲师,主要研究方向为无机多孔材料合成及应用,E-mail:h.wenke@gzhu.edu.cn。
