摘要
The outbreak of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which causes coronavirus disease 2019(COVID-19),has posed a tremendous threat to global health,resulting in over 510 million infections and at least 6.23 million deaths worldwide as of early May 2022.Extensive efforts to fight against the SARS-CoV-2 pandemic have accelerated the research and clinical development of various vaccines and neutralizing antibodies(NAbs)[1,2].However,SARS-CoV-2 has an exceptional ability to mutate and evade the human immune system,which highlights the surveillance of SARS-CoV-2 evolution to anticipate and facilitate a timely response to new variants that could impact viral transmissibility and the efficacy of vaccines and antibody therapies[3].
基金
This work was supported by the National Natural Science Foundation of China(32100123 and 32100751)
the Ministry of Science and Technology of China(2018YFA0507402).
作者简介
Chunyan Yi,These authors contributed equally;Xiaoyu Sun,These authors contributed equally;Zhiyang Ling,email:lingzhiyang@sibs.ac.cn;Bing Sun,bsun@sibs.ac.cn。
