摘要
目的:探讨抑郁症患者药物治疗依从性现状及其影响因素。方法:以随机抽样方式选择2020年2月-2021年10月就诊于吉安市第三人民医院和吉安市青原区人民医院的136例抑郁症患者,收集、整理资料,分析其药物治疗依从性现状及其影响因素。结果:136例抑郁症患者药物治疗依从性好40例(29.41%),药物治疗依从性差96例(70.59%)。单因素分析显示:药物治疗依从性差组和药物治疗依从性好组的服药时间、文化程度、家庭人均月收入、医疗费用支付方式、药物不良反应、医患关系情况比较,差异均有统计学意义(P<0.05)。药物治疗依从性差组和药物治疗依从性好组的年龄、居住地、性别、婚姻状况、合并高血压、合并糖尿病、合并冠心病情况比较,差异均无统计学意义(P>0.05)。多因素分析显示:文化程度高中及以下[β=0.847,OR=2.333,95%CI(1.026,5.306)]、服药时间>12个月[β=1.718,OR=5.571,95%CI(2.245,13.828)]、家庭人均月收入<3000元[β=1.195,OR=3.304,95%CI(1.422,7.677)]、有药物不良反应[β=1.022,OR=2.778,95%CI(1.297,5.951)]、医疗费用自费[β=0.995,OR=2.705,95%CI(1.083,6.756)]、医患关系差[β=2.109,OR=8.239,95%CI(1.048,64.749)]是抑郁症患者药物治疗依从性差的高危因素(P<0.05)。结论:抑郁症患者药物治疗依从性较差,其受服药时间、文化程度、家庭人均月收入、医疗费用支付方式、药物不良反应、医患关系影响。
Objective:To investigate the current status and influencing factors of drug treatment compliance in patients with depression.Method:A total of 136 patients with depression who were treated in Ji An Third People’s Hospital and Ji An Qingyuan District People’s Hospital from February 2020 to October 2021 were selected by random sampling,and the data were collected and organized to analyze the current status of their drug treatment compliance and its influencing factors.Result:Among the 136 patients with depression,40 cases(29.41%)had good compliance with drug treatment,and 96 cases(70.59%)had poor compliance with drug treatment.Univariate analysis showed that:there were statistically significant differences in medication duration,educational level,per capita monthly household income,payment method of medical expenses,adverse drug reactions and doctor-patient relationship between poor medication compliance group and good medication compliance group(P<0.05).There were no significant differences in age,residence,sex,marital status,hypertension,diabetes and coronary heart disease between poor medication compliance group and good medication compliance group(P>0.05).Multivariate analysis showed that:high school education or below[β=0.847,OR=2.333,95%CI(1.026,5.306)],duration of medication>12 months[β=1.718,OR=5.571,95%CI(2.245,13.828)],per capita monthly household income<3000 yuan[β=1.195,OR=3.304,95%CI(1.422,7.677)],adverse drug reactions[β=1.022,OR=2.778,95%CI(1.297,5.951)],out-of-pocket medical expenses[β=0.995,OR=2.705,95%CI(1.083,6.756)],poor doctor-patient relationship[β=2.109,OR=8.239,95%CI(1.048,64.749)]were high risk factors for poor medication compliance in patients with depression(P<0.05).Conclusion:The drug treatment compliance of patients with depression is poor,which is affected by medication time,education level,per capita monthly household income,payment method of medical expenses,adverse drug reactions,and doctor-patient relationship.
作者
涂艳
谢小云
TU Yan;XIE Xiaoyun(Ji An Third People's Hospital,Jiangxi Province,Ji'an 343000,China;不详)
出处
《中国医学创新》
CAS
2023年第1期107-111,共5页
Medical Innovation of China
关键词
抑郁症
药物不良反应
文化程度
治疗依从性
Depression
Adverse drug reactions
Educational level
Treatment compliance
作者简介
通信作者:涂艳。
