摘要
目的 探讨后肾腺瘤的影像学特征及其与临床、病理的相关性。资料与方法 回顾性分析2011年1月—2017年6月在联勤保障部队第九〇〇医院住院治疗的6例经手术病理证实的后肾腺瘤患者的临床表现、CT/MRI及病理资料,记录病灶的部位、大小、密度(信号)、强化方式及程度等,结合近期相关国内外研究,总结其影像学特征与病理的相关性。结果 6例患者中,男2例,女4例。6例病灶均为单肾单发,边界清,其中5例为实性肿块,CT平扫呈等及稍高密度,均未见钙化,增强扫描呈渐进性轻中度强化;1例为囊实性病灶合并囊壁点状钙化,实性部分呈稍高密度;增强扫描呈持续性中度强化。2例T1WI均呈等或稍低信号,T2WI上1例呈低信号,另1例呈混杂稍高信号,扩散加权成像2例信号均增高。免疫组化:6例WT-1、CD57均呈阳性,Ki-67均低表达(1%~10%),1例细胞角蛋白7呈局灶阳性。结论 后肾腺瘤影像学表现具有一定特征性,为单肾单发的实性肿块,CT平扫呈等或稍高密度,扩散加权成像呈高信号,增强扫描呈轻中度强化,但其最终确诊需要依靠病理检查及免疫组化。
Purpose To investigate the imaging features of metanephric adenoma(MA) and its correlation with clinical characteristics and pathological features. Materials and Methods The clinical, CT/MR images and pathological data of 6 patients with MA confirmed by surgery and pathology in the 900th Hospital of Joint Logistics Support Force from January 2011 to June 2017 were retrospectively analyzed.The location, size, density/signal, enhancement pattern and degree of the lesion were recorded, and recent literatures at home and abroad were further reviewed, and the correlations between imaging findings and pathological features were finally summarized. Results Of 6 patients,there were 2 males and 4 females. All lesions were presented with single renal parenchyma mass with clear boundary. Of 6 lesions, there were 5 solid lesions with iso-density or slightly high density on CT plain scan, progressive mild to moderate enhancement on contrast-enhanced scan without calcification, and 1 cystic-solid lesion with spotty calcification in cyst wall, the solid component showed slightly high density on CT plain scan and persistent moderate enhancement on CT enhanced scan. A total of 2 cases underwent MRI scan;two lesions showed isointensity or slightly hypointensity on T1WI;one lesion was hypointensity and the other one was mixed slightly hyperintensity on T2WI;two lesions showed high signal on diffusion weighted imaging(DWI). All lesions showed positive WT-1 and CD57, low expression of Ki-67(1%-10%) via immunohistochemistry. In addition, 1 case presented CK7 was focally positive. Conclusion The imaging characteristics of MA include single solid mass of unilateral kidney, iso or slightly high density on CT plain scan, high signal on DWI, and mild to moderate enhancement patterns, but the definitive diagnosis depends on pathological examination and immunohistochemistry.
作者
刘凯丽
罗超然
陈倩
肖慧
LIU Kaili;LUO Chaoran;CHEN Qian;XIAO Hui(Department of Radiology,the 900th Hospital of Joint Logistics Support Force,PLA,Fuzhou 350025,China)
出处
《中国医学影像学杂志》
CSCD
北大核心
2022年第12期1285-1289,1295,共6页
Chinese Journal of Medical Imaging
关键词
后肾腺瘤
磁共振成像
体层摄影术
X线计算机
病理学
外科
免疫组化
Metanephric adenoma
Magnetic resonance imaging
Tomography,X-ray computed
Pathology,surgical
Immunohistochemistry
作者简介
通信作者:肖慧.xiaohui855@163.com。
