摘要
赤霉酸(gibberellic acid)是应用非常广泛的植物生长激素,目前农业生产上应用的赤霉酸主要来自藤仓赤霉菌Gibberella fujikuroi液态发酵,但产量还远远不能满足市场需求。代谢组学(metabonomics)是系统生物学研究的重要分支,近年来在微生物领域得到广泛应用,并取得了重要进展。文中综述了赤霉酸的种类、生产、应用、研究历程;代谢组学的概念、优点、研究方法、赤霉酸测定;基因改造、非生物胁迫、前体物质对赤霉酸生物合成的影响等领域的国内外研究进展,并对赤霉酸高效合成相关的多组学联合应用前景进行了展望,以期为工业生产中赤霉酸产量的进一步提升提供思路。
Gibberellic acid(GA)is a widely-used hormone that governs plant growth.At present,GA used in agricultural production is mainly from the liquid fermentation of the fungus Gibberella fujikuroi,but the yield is far from meeting the market demand.Metabonomics,as an important branch of system biology,has attracted extensive attention and made significant progress in the field of microbiology in recent years.This paper reviews the research progress at home and abroad in the fields of the type,production,application,and research process of GA,the concept,advantage,research technique,determination of GA on metabonomics,and the effect of genetic modification,abiotic stress,precursors on the biosynthesis of GA.The combined application of multiple omics related to the efficient synthesis of GA has also been prospected.It provides ideas for the further improvement of GA production in industrial production.
作者
殷凯楠
吴酬飞
尹良鸿
林海萍
YIN Kainan;WU Choufei;YIN Lianghong;LIN Haiping(Local and National Joint Engineering Laboratory of Biopesticide High-efficient Preparation,Zhejiang Agriculture and Forestry University,Lin’an 311300,Zhejiang Province,China;College of Life Science,Huzhou University,Huzhou 313000,Zhejiang Province,China)
出处
《农药学学报》
CAS
CSCD
北大核心
2022年第6期1314-1326,共13页
Chinese Journal of Pesticide Science
基金
浙江省基础公益研究计划项目(LGG22C140001)
浙江省重点研发项目(2019C02024).
关键词
代谢组学
藤仓赤霉菌
赤霉酸
生物合成途径
metabonomics
Gibberella fujikuroi
gibberellic acid
biosynthetic pathway
作者简介
第一作者:殷凯楠,inshdar@qq.com;通信作者:尹良鸿,ylh4@163.com;通信作者:林海萍,zjlxylhp@163.com.
