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文拉法辛联合认知行为疗法对抑郁症巩固治疗期患者的影响 被引量:6

The Influence of Venlafaxine Combined with Cognitive Behavioral Therapy in the Consolidation Stage of Depression Patients
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摘要 目的 分析文拉法辛联合认知行为疗法对抑郁症巩固治疗期患者的影响。方法 围绕2021年3月至2021年12月郑州市第九人民医院收治的96例巩固治疗期抑郁症患者展开研究,并以随机抽样法为分组依据,将其分为对照组(N=48)及试验组(N=48),对照组仅接受文拉法辛治疗,试验组采取文拉法辛+认知行为疗法治疗。对比两组治疗有效率、焦虑自评量表、抑郁自评量表、生活质量量表评分波动情况、抑郁症复燃发生率。结果 试验组治疗有效率(95.83%)高于对照组(81.25%),差异有统计学意义(P <0.05);治疗前两组焦虑、抑郁评分对比,差异无统计学意义(P> 0.05),治疗后试验组两项评分均低于对照组,差异有统计学意义(P <0.05);治疗前两组生活质量评分对比,差异无统计学意义(P> 0.05),治疗后试验组生理、心理、社会、总体健康评分均高于对照组,差异有统计学意义(P <0.05);试验组患者抑郁症复燃率(6.25%)低于对照组(20.83%),差异有统计学意义(P <0.05)。结论 文拉法辛+认知行为疗法可显著改善巩固治疗期抑郁症患者抑郁状态,提升其生活质量,建议临床应用。 Objective To analyze the impact of Venlafaxine combined with cognitive behavioral therapy in the consolidation stage of depression patients.Methods A total of 96 consolidation stage of depression patients treated in our hospital from March 2021 to December 2021 were selected.According to random sampling method,patients were divided into control group(N=48,Venlafaxine)and trial group(N=48,Venlafaxine and cognitive behavioral therapy).The total effective rate,self-rating anxiety scale,self-rating depression scale,life quality scores,recurrence rate and Hamilton's depression scale were compared.Results The total effective rate in the trial group was higher than control group)(95.83%vs.81.25%),with signifiant difference(P<0.05);Before treatment,the anxiety and depression scores between groups were not significantly different(P>0.05);After treatment,the anxiety and depression scores in the trial group were lower than control group,with signifiant differences(P<0.05);Before treatment,the life quality scores between groups were not significantly different(P>0.05);After treatment,the physiological,mental,social and general health scores in the trial group were higher than control group,with signifiant differences(P<0.05);The recurrence rate in the trial group was lower than control group(6.25%vs.20.83%),with signifiant difference(P<0.05).Conclusion Venlafaxine combined with cognitive behavioral therapy can greatly ameliorate the depression states and life quality for consolidation stage of depression patients,the clinical application is recommended.
作者 韩娇 赵静 HAN Jiao;ZHAO Jing(Department of Psychology,Zhengzhou Ninth People's Hospital,Zhengzhou Henan 450000,China)
出处 《临床研究》 2022年第12期81-84,共4页 Clinical Research
关键词 文拉法辛 认知行为疗法 巩固治疗期 抑郁症 venlafaxine cognitive behavioral therapy consolidation stage depression
作者简介 韩娇(1987—),女,汉族,河南焦作人,住院医师,硕士研究生。研究方向:精神药理学方面。
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