摘要
目的研究成立胸痛中心(CPC)对ST段抬高型心肌梗死(STEMI)患者再灌注时间及预后的影响。方法采用回顾性分析方法,以2020年2月至2021年2月青岛市中医医院CPC成立后收治的62例STEMI患者为观察对象,设为研究组;以2019年1月至2020年1月CPC成立前收治的62例STEMI患者为观察对象,设为对照组。比较两组患者的再灌注时间[初次医疗接触至球囊扩张(FMC-to-B)时间、入门至球囊扩张(D-to-B)时间、FMC-to-B时间<120 min达标率、D-to-B时间<90 min达标率]、住院时间、住院费用与术后6个月左心室射血分数(LVEF)、不良心血管事件(MACE)发生率。结果研究组FMC-to-B、D-to-B时间与住院时间分别为(113.15±83.62)min、(83.69±46.85)min、(10.52±4.96)d,短于对照组[(153.28±85.16)min、(135.37±59.47)min、(12.41±5.58)d],FMC-to-B时间<120 min达标率、D-to-B时间<90 min达标率为72.58%、83.87%,高于对照组(48.39%、38.71%),住院费用为(3.70±0.96)万元,低于对照组[(4.11±1.00)万元],术后6个月LVEF水平、MACE发生率为(58.64±3.47)%、4.83%,低于对照组[(52.91±4.16)%、17.74%],差异均有统计学意义(P<0.05)。结论STEMI患者治疗中成立CPC可显著缩短其再灌注时间及住院时间,降低住院费用及MACE发生率,提升LVEF,改善预后。
Objective To investigate the effect of chest pain center(CPC)on reperfusion time node and prognosis in PATIENTS with ST-segment elevation myocardial infarction(STEMI).Methods A total of 62 STEMI patients treated after Qingdao Traditional Chinese Medicine Hospital CPC establishment from February 2020 to February 2021 were enrolled as study group by retrospective analysis.Meanwhile,62 STEMI patients admitted from January 2019 to January 2020 before the establishment of CPC were enrolled as the control group.The two groups were compared in terms of reperfusion time[time from initial medical contact to balloon dilation(FMC-to-B),time from entry to balloon dilation(D-to-B),compliance rate of FMC-to-B time<120 min,and D-to-B time<90 Min compliance rate],length of hospital stay,hospitalization costs and the incidence of left ventricular ejection fraction(LVEF)and adverse cardiovascular events(MACE)6 months after surgery.Results The FMC-to-B,D-to-B time and hospital stay in the study group were(113.15±83.62)min,(83.69±46.85)min,and(10.52±4.96)d,respectively,which were shorter than those in the control group[(153.28±85.16)min,(135.37±59.47)min,(12.41±5.58)d],the compliance rates of fMC-to-B time<120 min and D-to-B time<90 min were 72.58%,83.87%,which were higher than those in the control group(48.39%,38.71%),the cost of hospitalization was(3.70±0.96)ten thousand yuan,which was lower than that in the control group[(4.11±1.00)ten thousand yuan],and the LVEF level and the incidence of MACE at 6 months after surgery were(58.64±3.47)%and 4.83%,which were lower than those in the control group[(52.91±4.16)%and 17.74%],and the differences were statistically significant(P<0.05).Conclusion The establishment of CPC in STEMI patients can significantly shorten the reperfusion time and length of hospital stay,reduce the hospitalization cost and incidence of MACE,improve LVEF,and improve prognosis.
作者
武文辉
陈倩
王培翠
WU Wen-hui;CHEN Qian;WANG Pei-cui(Cardiovascular Division,Qingdao Traditional Chinese Medicine Hospital(Qingdao Haici Hospital),Qingdao Shandong 266000,China.;Functional Examination Section,Qingdao Traditional Chinese Medicine Hospital(Qingdao Haici Hospital),Qingdao Shandong 266000,China.)
出处
《临床和实验医学杂志》
2022年第20期2173-2176,共4页
Journal of Clinical and Experimental Medicine
基金
2021年山东省中医药科技项目(编号:2021Q056)。
关键词
ST段抬高型心肌梗死
胸痛中心
再灌注时间
预后
不良心血管事件
ST-segment elevation myocardial infarction
Chest pain center
Reperfusion time
The prognosis
Adverse cardiovascular events
作者简介
通讯作者:王培翠,E-mail:hiserwpc@163.com。