摘要
目的:探讨内镜下低温等离子射频消融术治疗早期声门型喉癌患者效果。方法:回顾性分析2020年1-12月佳木斯市东风区人民医院收治的100例早期声门型喉癌患者的临床资料,依据手术治疗方案的差异将患者分成对照组和研究组,每组50例。对照组采用喉裂开手术治疗,研究组采用内镜下低温等离子射频消融术治疗。比较两组视觉模拟评分法(VAS)评分、术后住院时间、术中出血量、手术时间、术后并发症发生情况、嗓音声学检测[谐噪比(HNR)、振幅微扰(Shimmer)、基频微扰(Jitter)]及生活质量评分。结果:研究组术后3 d的VAS评分低于对照组,术中出血量少于对照组,术后住院时间和手术时间均短于对照组,差异均有统计学意义(P<0.05)。研究组并发症发生率低于对照组(P<0.05)。术后7、30 d,研究组HNR均高于对照组,研究组Shimmer、Jitter均低于对照组,差异均有统计学意义(P<0.05)。术后30 d、术后半年、术后1年,研究组生活质量评分均高于对照组(P<0.05)。结论:内镜下低温等离子射频消融术治疗早期声门型喉癌有较高的安全性,患者嗓音功能能够更快、更好恢复,患者术后疼痛程度能够得到有效减少,生活质量得到显著改善,临床治疗效果确切,值得应用。
Objective:To investigate the effect of endoscopic low-temperature plasma radiofrequency ablation in the treatment of early glottic laryngeal cancer.Method:The clinical data of 100 patients with early glottic laryngeal cancer admitted to Jiamusi Dongfeng District People’s Hospital from January to December 2020 were retrospectively analyzed,the patients were divided into control group and study group according to the difference of surgical treatment plan,with 50 cases in each group.The control group was treated with laryngeal dehiscence operation,and the study group was treated with endoscopic low-temperature plasma radiofrequency ablation.The visual analogue scale(VAS)scores,postoperative hospital stay,intraoperative blood loss,operation time,postoperative complications,voice acoustic detection[harmonic noise ratio(HNR),amplitude perturbation(Shimmer),fundamental frequency perturbation(Jitter)]and quality of life scores were compared between the two groups.Result:The VAS score of the study group was lower than that of the control group 3 d after operation,the intraoperative blood loss of the study group was less than that of the control group,the postoperative hospital stay and operation time of the study group were shorter than those of the control group,the differences were statistically significant(P<0.05).The complication rate of the study group was lower than that of the control group(P<0.05).At 7 and 30 d after operation,HNR of the study group were higher than those of the control group,Shimmer and Jitter of the study group were lower than those of the control group,the differences were statistically significant(P<0.05).The scores of quality of life of the study group were higher than those of the control group at 30 d,6 months and 1 year after operation(P<0.05).Conclusion:Endoscopic low-temperature plasma radiofrequency ablation for patients with early glottic laryngeal cancer has high safety,the voice function of patients can recover faster and better,the degree of postoperative pain can be effectively reduced,the quality of life can be significantly improved,and the clinical treatment effect is accurate,which is worthy of application.
作者
苏钰茗
牟基伟
SU Yuming;MOU Jiwei(Jiamusi Dongfeng District People’s Hospital,Heilongjiang Province,Jiamusi 154005,China;不详)
出处
《中国医学创新》
CAS
2022年第28期68-73,共6页
Medical Innovation of China
关键词
内镜下低温等离子射频消融术
早期声门型喉癌
语音功能
Endoscopic low-temperature plasma radiofrequency ablation
Early glottic laryngeal cancer
Voice function
作者简介
通信作者:苏钰茗。
