摘要
目的:了解体检人群高血压检出情况,为高血压的防治提供参考。方法:选取2019—2021年在成都市某三级甲等医院体检且年龄≥18岁的25064例健康体检者作为研究对象,收集一般人口学资料、体格检查及实验室检查指标,筛选高血压疾病发生的危险因素,构建风险预测模型。结果:25064例健康体检者中,高血压检出率为11.7%。二元Logistic回归分析显示,工作状况为在职、奶制品摄入充足为高血压的保护因素(OR=0.681、0.582,P<0.05),年龄增长、有高血压家族史、饮酒、血脂异常、超重或肥胖、冠心病为高血压的独立危险因素(OR=3.319、5.765、20.276、4.461、1.486、1.514、2.713、2.894,均P<0.05)。疾病风险模型中各因素赋分如下:工作状况为在职1分,年龄40~<60岁3分、60~<80岁5分、≥80岁8分,有高血压家族史4分,奶制品摄入充足1分,饮酒1分,血脂异常1分,超重或肥胖3分,有冠心病4分。构建的风险预测模型预测高血压的受试者工作特征(ROC)曲线下面积(AUC)为0.864(95%CI:0.861~0.872),灵敏度、特异度分别为0.968和0.496。结论:构建高血压疾病预测模型对健康体检人群具有较好的预测能力,风险评估模型可以准确地预测高血压发病情况。
Objective:To understand the detection of hypertension in the physical examination population and to provide reference for the prevention and treatment of hypertension.Methods:25,064 cases of physical examination in a grade A tertiary hospital in Chengdu and aged≥18 years old from 2019-2021 were selected as study subjects,and general demographic data,physical examination and laboratory test indices were collected to screen risk factors for the occurrence of hypertension and construct a risk prediction model.Results:The detection rate of hypertension was 11.7%among 25,064 health checkups.Binary logistic regression analysis showed that work status as employed and adequate daily intake of dairy products were protective factors for hypertension(OR=0.681,0.582,P<0.05),and increasing age,family history of hypertension,alcohol consumption,dyslipidemia,overweight or obesity,and coronary heart disease were independent risk factors for hypertension(OR=3.319,5.765,20.276,4.461,1.486,1.514,2.713,2.894,all P<0.05).The factors in the disease risk model were assigned the following scores:work status as employed 1,age group 40 to<60 years old 3,60 to<80 years old5,≥80 years old 8,family history of hypertension 4,adequate intake of dairy products 1,alcohol consumption 1,dyslipidemia 1,overweight or obesity 3,and coronary heart disease 4.The area under the receiver operating characteristic(ROC)curve(AUC)of the constructed risk prediction model for hypertension was 0.864(95%CI:0.861-0.872),and the sensitivity and specificity were 0.968 and 0.496,respectively.Conclusion:The constructed hypertension disease prediction model has good predictive ability for the physical examination population,and the risk assessment model can accurately predict the onset of hypertension.
作者
何昭霞
吴俊林
李超
张文龙
杨辰
涂孟怡
黄霞
高茹
He Zhaoxia;Wu Junlin;Li Chao;Zhang Wenlong;Yang Chen;Tu Mengyi;Huang Xia;Gao Ru(Chengdu Wenjiang District People’s Hospital,Chengdu 611130,China;Sichuan Mental Health Center Mianyang Third People’s Hospital,Mianyang 621000,China;Private Sichuan Tianyi College,Mianzhu 618209,China)
出处
《广西医科大学学报》
CAS
2022年第9期1486-1492,共7页
Journal of Guangxi Medical University
基金
成都市卫生健康委员会2020年医学科研立项课题(No.2020039)。
作者简介
共同第一作者:吴俊林;通信作者:高茹,E-mail:154475957@qq.com。
