摘要
目的探究足月新生儿窒息抢救时选择不同起始浓度氧复苏方案的作用。方法选择南阳医学高等专科学校第一附属医院2020年3月至2022年3月收治的62例足月新生儿窒息患儿。按照治疗方法不同分为常规组(31例),试验组(31例),将21%初始氧浓度治疗应用于常规组患儿中,将40%初始氧浓度治疗应用于试验组患儿中。针对每组患儿临床指标、各时期心室率、血气监测指标、新生儿Apgar评分、肌酸激酶同工酶水平、肌钙蛋白水平、治疗效果、新生儿神经行为测定(NBNA)评分进行比较。结果试验组患儿开始啼哭时间、建立自主呼吸时间、血氧饱和度>90%的时间及生命体征恢复平稳的时间均短于常规组,差异有统计学意义(P<0.05)。同组组内治疗后心室率及血氧分压水平均高于治疗前,二氧化碳分压水平相较治疗前低;治疗后试验组患儿心室率及血氧分压水平均高于常规组,二氧化碳分压水平相较常规组低,差异有统计学意义(P<0.05)。试验组5 min、10 min新生儿Apgar评分相较常规组高,差异有统计学意义(P<0.05)。同组组内治疗后肌酸激酶同工酶及肌钙蛋白水平相较治疗前低,治疗后试验组患儿肌酸激酶同工酶及肌钙蛋白水平相较常规组低,差异有统计学意义(P<0.05)。试验组与常规组治疗有效率依次是93.55%、74.19%,差异有统计学意义(P<0.05)。同组组内治疗后NBNA得分相较治疗前高,治疗后试验组患儿NBNA得分相较常规组高,差异有统计学意义(P<0.05)。结论足月新生儿窒息抢救时选择40%初始氧浓度治疗,能够缩短治疗时间,调节心室率和血气监测指标,提高其神经行为功能及新生儿Apgar评分,强化治疗效果,发挥重要作用。
Objective To explore the effect of different initial concentrations of oxygen resuscitation in the rescue of fullterm neonatal with asphyxia.Methods A total of 62 full-term neonates with asphyxia admitted to the First Affiliated Hospital of Nanyang Medical College from March 2020 to March 2022 were selected.According to different treatment methods,they were divided into a routine group(31 cases)and a test group(31 cases).The 21%initial oxygen concentration was applied to the routine group,and the 40%initial oxygen concentration was applied to the test group.The clinical indicators,ventricular rate,blood gas monitoring indicators,neonatal Apgar score,creatine kinase isoenzyme level,troponin level,treatment effect,and neonatal neurobehavioral measurement(NBNA)score were compared in each group.Results The time to start crying,the time to establish spontaneous breathing,the time of blood oxygen saturation>90%,and the time of vital signs returning to stable in the test group were shorter than those in the routine group,and the differences were statistically significant(P<0.05).After treatment,the ventricular rate and blood oxygen partial pressure were higher than those before treatment,and the carbon dioxide partial pressure was lower than that before treatment in the same group.After treatment,the ventricular rate and blood oxygen partial pressure in the test group were higher than those in the routine group,and the carbon dioxide partial pressure level was lower than that in the routine group,and the differences were statistically significant(P<0.05).The Apgar scores of neonates in the test group at 5 min and 10 min were higher than those in the routine group,and the differences were statistically significant(P<0.05).After treatment,the levels of creatine kinase isoenzyme and troponin in the same group were lower than those before treatment.After treatment,the levels of creatine kinase isoenzyme and troponin in the test group were lower than those in the routine group,and the differences were statistically significant(P<0.05).The effective rates of the test group and the routine group were 93.55%and 74.19%respectively,and the difference was statistically significant(P<0.05).The NBNA score in the same group after treatment was higher than that before treatment,and the NBNA score in the test group was higher than that in the routine group after treatment,and the difference was statistically significant(P<0.05).Conclusion The 40%initial oxygen concentration in the rescue of full-term neonates with asphyxia can shorten the treatment time,regulate ventricular rate and blood gas monitoring indexes,improve the neurobehavioral function and neonatal Apgar score,and strengthen the treatment effect.
作者
郭晓征
GUO Xiaozheng(Neonatal Intensive Care Unit,The First Affiliated Hospital of Nanyang Medical College,Nanyang Henan 473000,China)
出处
《临床研究》
2022年第11期50-53,共4页
Clinical Research
关键词
新生儿窒息
足月
复苏方案
起始浓度
血氧饱和度
神经行为
neonatal asphyxia
full-term
recovery schemes
initial concentration
oxygen saturation
neurobehavioral
作者简介
郭晓征(1989—),女,汉族,河南南阳人,住院医师,大专。研究方向:新生儿相关方面。
