摘要
目的探究3.0T磁共振(MRI)多参数成像在乳腺癌新辅助化疗(NAC)疗效中的应用价值。方法选取2020年1月至2022年1月新余市人民医院收治的60例乳腺癌患者临床资料进行回顾性分析,按照NAC疗效分为显效组23例与非显效组37例,两组均行MRI多参数检查。比较两组肿瘤最大径线(LD)、表观扩散系数(ADC)、早期强化率(E)、最大强化率(PE)的变化率(ΔLD、ΔADC、ΔE、ΔPE),并采用ROC曲线对NAC疗效中采用MRI多参数变化率判断的应用价值进行分析。结果显效组患者NAC后的ΔLD、ΔADC、ΔE、ΔPE均高于非显效组,差异有统计学意义(P<0.05)。ROC曲线分析显示,MRI多参数变化率联合预测的曲线下面积(0.871)及灵敏度(91.30%)最高,ΔADC预测的特异度最高(91.89%)。结论对乳腺癌新辅助化疗患者采用3.0T磁共振多参数成像评估疗效的临床价值较高,是临床重要的预测指标。
Objective To explore the application value of 3.0T magnetic resonance imaging(MRI)multiparameter imaging in the efficacy of neoadjuvant chemotherapy(NAC)in breast cancer.Methods The clinical data of 60 patients with breast cancer admitted to Xinyu People′s Hospital from January 2020 to January 2022 were retrospectively analyzed.According to the efficacy of NAC,the patients were divided into significant effect group(n=23)and non-significant effect group(n=37).Both groups underwent multi-parameter MRI examination.The changes of maximum diameter(LD),apparent diffusion coefficient(ADC),early enhancement rate(E)and maximum enhancement rate(PE)(ΔLD,ΔADC,ΔE,ΔPE)were compared between the two groups.The ROC curve was used to analyze the application value of MRI multi-parameter change rate in NAC efficacy.Results After NAC,ΔLD,ΔADC,ΔE,andΔPE in the significant effect group were higher than those in the non-significant effect group,and the differences were statistically significant(P<0.05).ROC curve analysis showed that the area under the curve(0.871)and sensitivity(91.30%)of the combined prediction of MRI multi-parameter change rate were the highest,and the specificity ofΔADC prediction was the highest(91.89%).Conclusion The clinical value of 3.0T magnetic resonance multiparameter imaging in evaluating the efficacy of neoadjuvant chemotherapy for breast cancer patients is high,and it is an important clinical predictor.
作者
熊淑红
阮玖根
肖琼
丁瑶
XIONG Shuhong;RUAN Jiugen;XIAO Qiong;DING Yao(Department of Image Center,Xinyu People′s Hospital,Jiangxi Province,Xinyu 338025,China)
出处
《中国当代医药》
CAS
2022年第28期148-150,共3页
China Modern Medicine
基金
江西省新余市科技计划项目(20213090879)。
关键词
乳腺癌
磁共振成像
新辅助化疗
临床价值
Breast cancer
Magnetic resonance imaging
Neoadjuvant chemotherapy
Clinical value
作者简介
熊淑红(1983-),女,江西吉安人,硕士,研究方向:影像诊断。
