摘要
目的探究CT脑灌注参数脑血容量(sCBV)、相对脑血流量(sCBF)、相对平均通过时间(sMTT)、相对达峰时间(sTTP)对颈动脉狭窄患者术后疗效的预测价值。方法选取2017年1月至2021年1月榆林市第二医院收治的31例颈动脉狭窄术后过度灌注综合征患者作为观察组,同时选取未发生过度灌注综合征的30例患者作为对照组。对过度灌注综合征形成的因素进行单因素分析,对单因素分析存在明显差异的指标进行多因素Logistic回归分析。结果两组患者在高血压、高血脂、年龄分布、糖尿病合并情况、sCBV、sCBF、sMTT、sTTP水平间比较差异均具有统计学意义(P<0.05);多因素Logistic回归分析结果显示,高血压、糖尿病、sCBF≥1.2 mm、sCBV≥1.0 mm、sMTT≥1.3 cm/s、sTTP≥1.2 mL/m2是影响颈动脉狭窄患者的脑过度灌注综合征发生的独立危险因素(P<0.05)。结论CT脑灌注参数能潜在预测颈动脉狭窄患者术后疗效,高血压、糖尿病、sCBF、sCBV、sMTT、sTTP是颈动脉狭窄患者发生脑过度灌注综合征的独立危险因素。
Objective To explore the predictive value of CT cerebral perfusion parameters cerebral blood volume(sCBV),relative cerebral blood flow(sCBF),relative mean transit time(sMTT),and relative time to peak(sTTP)on the postoperative efficacy of patients with carotid stenosis.Methods Thirty-one patients with postoperative hyperperfusion syndrome of carotid stenosis treated in Yulin Second Hospital from January 2017 to January 2021 were selected as the observation group,and 30 patients without hyperperfusion syndrome were selected as the control group.The factors of hyperperfusion syndrome were analyzed by univariate analysis,and the indexes with significnat differences in univariate analysis were analyzed by multivariate logistic regression.Results Univariate analysis showed that there were significant differences in the levels of hypertension,hyperlipidemia,age distribution,diabetes mellitus,sCBV,sCBF,sMTT,and sTTP between the two groups(P<0.05).Multivariate logistic regression analysis showed that hypertension,diabetes,sCBF≥1.2 mm,sCBV≥1.0 mm,sMTT≥1.3 cm/s,sTTP>1.2 mL/m2 were independent risk factors for cerebral hyperperfusion syndrome in patients with carotid artery stenosis(P<0.05).Conclusion CT cerebral perfusion parameters can potentially predict the postoperative efficacy of patients with carotid stenosis.Hypertension,diabetes,sCBF,sCBV,sMTT,and sTTP are independent risk factors for cerebral hyperperfusion syndrome in patients with carotid stenosis.
作者
杜彦挺
杜光勇
贾喆
王晓溪
贺利霞
DU Yan-ting;DU Guang-yong;JIA Zhe;WANG Xiao-xi;HE Li-xia(WardⅡ,Department of Neurosurgery,Yulin Second Hospital,Yulin 719000,Shaanxi,CHINA;Image Center,Yulin Second Hospital,Yulin 719000,Shaanxi,CHINA)
出处
《海南医学》
CAS
2022年第17期2241-2244,共4页
Hainan Medical Journal
关键词
脑灌注参数
颈动脉狭窄
脑过度灌注综合征
独立危险因素
Cerebral perfusion parameters
Carotid stenosis
Cerebral hyperperfusion syndrome
Independent risk factor
作者简介
通讯作者:杜彦挺,E-mail:479188865@qq.com。
