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探讨胶体果胶铋颗粒治疗小儿慢性胃炎疗效转归及安全性 被引量:3

Investigation on the Efficacy,Outcome and Safety of Colloidal Bismuth Pectin Granules in the Treatment of Children with Chronic Gastritis
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摘要 目的探究分析在对小儿慢性胃炎患儿进行治疗时应用阿莫西林、奥美拉唑、克拉霉素、果胶铋的效果。方法选择2018年5月—2021年5月贵州医科大学附属白云医院门诊中自愿入组的100例确诊为小儿慢性胃炎的患儿作为研究对象,随机分为对照组(n=50)以及研究组(n=50),开展前瞻性对照实验。对照组患儿应用奥美拉唑、阿莫西林、克拉霉素进行治疗;研究组患儿在对照组的用药基础上增加果胶铋治疗,对比两组患儿的病情恢复状况,对治疗前后患儿的生活质量评分进行评估。结果治疗后,研究组患儿的心理状态、社会功能及胃肠道功能评分均优于对照组,研究组患儿体内的炎性因子水平低于对照组,差异有统计学意义(P<0.05)。研究组患儿的治疗总有效率为94.00%高于对照组的76.00%,差异有统计学意义(χ2=6.353,P<0.05)。结论在对小儿慢性胃炎患儿进行治疗时,将奥美拉唑、阿莫西林、克拉霉素、果胶铋应用于患儿的治疗中有助于提升患儿的治疗效果,提升患儿的生活质量,降低患儿的炎性因子水平,具有良好的可应用价值。 Objective To explore and analyze the efficacy of amoxicillin,omeprazole,clarithromycin and bismuth pectin in the treatment of children with chronic gastritis.Methods A total of 100 patients diagnosed with chronic gastritis in children who were voluntarily enrolled in the outpatient clinic of Baiyun Hospital Affiliated to Guizhou Medical University from May 2018 to May 2021 were selected as the research subjects,and were randomly divided into the control group(n=50)and the study group(n=50).The patients in the control group were treated with omeprazole,amoxicillin and clarithromycin;the patients in the study group were treated with bismuth pectin on the basis of the medication in the control group.The condition recovery status of the two groups was compared,and the quality of life score of the children before and after treatment was evaluated.Results After treatment,the psychological state,social function and gastrointestinal function scores of the children in the study group were better than those in the control group,and the levels of inflammatory factors in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).The total effective rate of the study group was 94.00%higher than 76.00%of the control group,and the difference was statistically significant(χ2=6.353,P<0.05).Conclusion In the treatment of children with chronic gastritis,the application of omeprazole,amoxicillin,clarithromycin and bismuth pectin in the treatment of children can help to improve the treatment effect of children,improve the quality of life of children,reduce the level of inflammatory factors of children,which has good application value.
作者 陈湘燕 CHEN Xiangyan(Baiyun Hospital Affiliated to Guizhou Medical University,Guiyang,Guizhou Province,550014 China)
出处 《世界复合医学》 2022年第8期154-157,共4页 World Journal of Complex Medicine
关键词 胶体果胶铋 小儿慢性胃炎 疗效分析 治疗方案 Colloidal bismuth pectin Children with chronic gastritis Efficacy analysis Treatment plan
作者简介 陈湘燕(1981-),女,苗族,本科,副主任医师,研究方向为小儿内科。
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