摘要
目的:探究未合并心脑血管疾病的阻塞性睡眠呼吸暂停综合征患者和颈动脉粥样硬化的相关性。方法:选取2019年1月至2021年1月在北京市平谷区岳协医院康复科收治的无心脑血管疾病的阻塞性呼吸睡眠暂停综合征患者71例作为研究对象,根据是否发生颈动脉粥样硬化(CAS)分为CAS组(n=31)和无CAS组(n=40),观察并测定2组患者OAS指标、血糖指标,分析阻塞性睡眠呼吸暂停和颈动脉粥样硬化的相关性。结果:2组患者的血糖指标水平比较,差异无统计学意义(P>0.05),CAS组患者AHI为(21.08±8.85)次/h,高于无CAS组的(18.21±7.66)次/h,CAS组患者平均SpO 2为(92.64±6.93)%,低于无CAS组的(18.21±7.66)%,CAS组患者AHI≥15次/h比例为66.67%,高于无CAS组45.00%,CAS组患者CIMT水平为(1.12±0.36)mm,高于无CAS组(0.88±0.31)mm,以上指标2组比较,差异均有统计学意义(均P<0.05);患者AHI次数和AHI≥15次/h与CAS成正相关(r=0.138,P<0.05),平均SpO 2水平与CAS呈负相关(r=-0.282,P<0.05)。结论:无心脑血管疾病的阻塞性睡眠呼吸暂停综合征患者和颈动脉粥样硬化存在相关性,在临床诊断治疗中应予以高度重视,以期改善患者生命质量,改善预后。
Objective:To explore the correlation between obstructive sleep apnea and carotid atherosclerosis in patients without cardiovascular and cerebrovascular diseases.Methods:Ffrom January 2019 to January 2021,71 patients with OSAS without cardiovascular and cerebrovascular diseases in Pinggu District Yuexie Hospital of Beijing were selected and divided into as group(31 cases)and non as group(40 cases)according to the occurrence of cervical as.The indexes of OSAS and blood glucose were observed and measured,and the correlation between obstructive sleep apnea and carotid atherosclerosis was analyzed.Results:Comparison of blood glucose index levels of patients in group 2,There was no significant difference(P>0.05),The AHI of patients in the CAS group was(21.08±8.85)times/h,Higher than(18.21±7.66)without CAS group/h,The mean SpO 2 of patients in the CAS group was(92.64±6.93)%,Less than that in the no-CAS group(18.21±7.66)%,The proportion of 15 times/h of AHI in the CAS group was 66.67%,45.00%without CAS,The CIMT level of the patients in the CAS group was(1.12±0.36)mm,Above mm above CAS group(0.88±0.31),Two comparison of the above indicators,All the differences were significant(all P<0.05);The number of patient AHI and AHI 15 times/h were positively associated with CAS(r=0.138,P<0.05),The mean SpO 2 levels were inversely correlated with CAS(r=-0.282,P<0.05).Conclusion:There is a correlation between obstructive sleep apnea and carotid atherosclerosis in patients without cardiovascular and cerebrovascular diseases,which should be paid great attention in clinical diagnosis and treatment,in order to improve the quality of life and prognosis of patients.
作者
王晓虎
张磊
WANG Xiaohu;ZHANG Lei(Department of Rehabilitation,Pinggu District Yuexie Hospital of Beijing,Beijing 101200,China;Department of Neurosurgery,Jingdong Medical District,PLA General Hospital,Beijing 101149,China)
出处
《世界睡眠医学杂志》
2022年第7期1347-1350,共4页
World Journal of Sleep Medicine
作者简介
通信作者:王晓虎,E-mail:banlanxiaohu@163.com。
