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氨甲环酸预防高危剖宫产产妇产后出血的效果及其对凝血功能的影响分析 被引量:4

Effect of Tranexamic Acid on Prevention of Postpartum Hemorrhage in High-risk Cesarean Section Women and Its Effect on Coagulation Function
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摘要 目的探讨氨甲环酸预防高危剖宫产产妇产后出血的效果,及其对产妇凝血功能的影响。方法选取盘锦市中心医院妇产科2019年4月—2020年12月收治的高危剖宫产产妇80例,随机分为对照组和观察组,对照组采取产后出血常规预防方案,观察组则在对照组的基础上在产前给予氨甲环酸,比较两组预防产后出血的效果和凝血功能。结果观察组术中、产后2 h、产后24 h出血量均少于对照组,恶露持续时间短于对照组,缩宫素用量少于对照组,宫缩持续时间长于对照组,宫底下降速度快于对照组,治疗转归率高于对照组,产后2 h凝血功能指标优于对照组,差异均具有统计学意义(P<0.05)。结论产前给予氨甲环酸能预防高危剖宫产产妇产后出血,减少出血量,且能够改善产妇的凝血功能。 Objective To explore the effect of tranexamic acid on preventing postpartum hemorrhage in high-risk cesarean section women and its effect on coagulation function.Methods A total of 80 high-risk cesarean section parturients treated in the department of obstetrics and gynecology of Panjin Central Hospital from April 2019 to December 2020 were randomly divided into control group and observation group.The control group was treated with routine prevention of postpartum hemorrhage,while the observation group was given tranexamic acid before delivery on the basis of the control group.The effect of preventing postpartum hemorrhage and coagulation function of the two groups were compared.Results The amount of bleeding during operation,2 hours postpartum and 24 hours postpartum in the observation group was significantly less than that in the control group,the duration of lochia was significantly shorter than that in the control group,the dosage of oxytocin was significantly less than that in the control group,the duration of uterine contraction was significantly longer than that in the control group,the decline rate of uterine fundus was significantly faster than that in the control group,the treatment outcome rate was significantly higher than that in the control group,and the coagulation function index at 2 hours postpartum was significantly better than that in the control group(all P<0.05).Conclusion Prenatal administration of tranexamic acid can prevent postpartum hemorrhage in high-risk cesarean section,reduce the amount of bleeding,and improve the coagulation function of pregnant women.
作者 邵文佳 SHAO Wenjia(Maternity Hospital District,Panjin Central Hospital,Panjin 124000,Liaoning Province,China)
出处 《中国实用乡村医生杂志》 2022年第5期52-54,59,共4页 Chinese Practical Journal of Rural Doctor
关键词 高危剖宫产孕妇 产后出血 预防 氨甲环酸 效果 凝血功能 High-risk Cesarean Section Women Postpartum Hemorrhage Prevention Tranexamic Acid Effect Coagulation Function
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