摘要
目的探讨急诊冠状动脉介入治疗(PCI)急性心肌梗死(AMI)青年患者的临床疗效。方法754例AMI患者根据年龄分为青年组(≤40岁,62例)与中老年组(>40岁,692例),两组患者均在发病后24 h内进行急诊PCI,比较两组患者的临床资料、辅助检查结果、冠脉病变情况及住院期间主要不良心脑血管病事件(MACCE)情况。结果青年组的高脂血症例数、BMI、心室率、左室射血分数(LVEF)、GRACE评分与中老年组比较,差异均有统计学意义(P均<0.05)。青年组的BNP、肌钙蛋白I、D二聚体明显低于中老年组,AST、TG水平明显高于中老年组,差异有统计学意义(P<0.05)。青年组冠脉多支血管病变明显少于中老年组,差异有统计学意义(P<0.05)。两组住院期间的MACE事件、大出血、死亡率比较,差异无统计学意义(P>0.05)。结论青年组AMI患者行急诊PCI相对安全,其中肥胖、高脂血症、单支血管病变多见,心衰、猝死发生率低。
Objective To investigate the clinical effect of emergent percutaneous coronary intervention(PCI)in young patients with acute myocardial infarction(AMI).Methods 754 AMI patients were divided into the young group(≤40 years old,62 cases)and the middle-aged and elderly group(>40 years old,692 cases)according to their age,and emergent PCI was performed in both groups within 24 hours after onset.The clinical data,auxiliary examination results,coronary artery lesions and major adverse cardiovascular and cerebrovascular disease events(MACCE)during hospitalization were compared between the two groups.Results There were significant differences in the number of hyperlipidemia cases,BMI,ventricular rate,left ventricular ejection fraction(LVEF)and GRACCE score between the young group and the middle-aged and elderly group(all P<0.05).The levels of BNP,troponin I and D dimer in young group were significantly lower than those in middle-aged and elderly group,and the levels of AST and TG were significantly higher than those in middle-aged and elderly group,with statistical significance(P<0.05).The number of coronary multi vessel lesions in the young group was significantly less than that in the middle-aged and elderly group,with statistical significance(P<0.05).There was no significant difference in mace events,massive hemorrhage and mortality between the two groups(P>0.05).Conclusion It is relatively safe for young patients with AMI to undergo emergent PCI,among which obesity,hyperlipidemia and single vessel disease are more common,and the incidence of heart failure and sudden death is low.
出处
《浙江临床医学》
2022年第6期870-872,共3页
Zhejiang Clinical Medical Journal
关键词
急性心肌梗死
青年
急诊冠脉介入治疗
临床疗效
Acute myocardial infarction
Youth
Emergent percutaneous coronary intervention
Clinical efficacy
