摘要
目的:探究两种剂量数字减影血管造影(DSA)用于异位妊娠子宫动脉栓塞介入治疗效果及放射毒副反应情况.方法:取2017年4月-2019年12月在本院诊治的子宫异位妊娠患者100例,随机数字表法分为两组各50例,均行DSA子宫动脉栓塞介入治疗,术中分别采用标准剂量DSA模式(标准剂量组)或低剂量DSA模式(低剂量组),比较两组治疗效果及放射毒副反应.结果:两组手术时间、术中出血量、术后出血量、住院时间均无差异,患者曝光时间标准剂量组(6.97±1.92min)与低剂量组(7.42±1.98min)无差异(P>0.05),辐射剂量标准剂量组(22.19±6.88 mGy)高于低剂量组(10.29±3.13mGy)(P<0.05);DSA图像质量标准剂量组优占84.0%、良占16.0%,低剂量组优占82.0%、良占18.0%,两组无差异(P>0.05).两组术后包块直径、血清β-HCG恢复时间、月经恢复时间均无差异(P>0.05).术后出血量标准剂量组(102.31±22.42ml)与低剂量组(99.82±20.37ml)无差异,两组肝功能异常、胃肠道反应、口腔溃疡、对比剂外渗、对比剂过敏等毒副反应发生率均无差异(均P>0.05).结论:宫颈异位妊娠子宫动脉栓塞介入治疗中,低剂量DSA模式所获得图像质量、手术指标、恢复效果及毒副反应等方面与标准剂量相当,但可显著减少辐射剂量,有助于降低DSA对患者机体损害.
Objective: To compare the clinical effects and radiotoxic side effects of two doses of digital subtraction angiography(DSA) in uterine artery embolization for the interventional treatment of ectopic pregnancy. Methods: A total of 100 patients with ectopic pregnancy who accepted interventional treatment of uterine artery embolization were selected and were divided into two groups(50 cases in each group) by random numbers table from April 2017 to December 2019. The patients in group A were given standard dose DSA mode and the patients in group B were given low dose DSA mode. The therapeutic effect and radiation toxicity of the patients were compared between the two groups. Results: There were no significant differences in the operative time, the intraoperative blood loss, the postoperative blood loss, and the hospital stay time of the patients between the two groups. There was no significant difference in the radiation exposure time(6.97±1.92 min vs. 7.42±1.98 min) of the patients between the two groups(P>0.05). The radiation dose of the patients in group A(22.19± 6.88 mGy) was significantly higher than that(10.29±3.13 mGy) of the patients in group B(P<0.05). The rates of excellent and good quality of DSA image of the patients in group A were 84.0% and 16.0%, which had no significant different from those(82.0% and 18.0%) of the patients in group B(P>0.05). There were no significant differences in the postoperative mass diameter, the recovery time of serum β-HCG level,and the menstrual recovery time of the patients between the two groups(P>0.05).There was no significant difference in the postoperative blood loss(102.31±22.42 ml vs.99.82±20.37ml)of the patients between the two groups(P>0.05).There were no significant differences in the incidences of liver dysfunction,gastrointestinal reaction,oral ulcer,contrast agent extravasation,contrast agent allergy,and other toxic reactions of the patients between the two groups(P>0.05).Conclusion:In the interventional treatment of uterine artery embolization for ectopic pregnancy,the image quality,surgical indicators,recovery effect,and toxic and side effects,and other index of the lowdose DSA mode are equivalent to those of the standard dose DSA,and which can significantly reduce the radiation dose and reduce DSA damage to the patient’s body.
作者
王磊
邹霞
林斌
唐孝华
WANG Lei;ZOU Xia;LIN Bin;TANG Xiaohua(903 Hospital,Jiangyou,Sichuan Province,621700;AVIC 363 Hospital of Chengdu,Chengdu,Sichuan Province)
出处
《中国计划生育学杂志》
2022年第7期1525-1528,1533,共5页
Chinese Journal of Family Planning
关键词
宫颈异位妊娠
子宫动脉栓塞术
不同辐射剂量
数字减影血管造影
临床疗效
毒副反应
Cervical ectopic pregnancy
Uterine artery embolization
Different radiation doses
Digital subtraction angiography
Clinical efficacy
Toxic and side effects
