地塞米松结合卡前列素氨丁三醇治疗高危妊娠产妇产后出血的临床疗效被引量：6

Clinical Efficacy of Dexamethasone Combined with Carboprost Tromethamine in the Treatment of Postpartum Hemorrhage in High-risk Pregnant Women

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摘要目的研究高危妊娠产妇采用地塞米松结合卡前列素氨丁三醇对于产后出血的效果。方法回顾性选取2016年12月—2018年12月该院收治的210例高危妊娠产妇为研究对象,根据治疗方法不同分成研究组和参照组,各105例。参照组注射卡前列素氨丁三醇进行治疗,研究组在参照组的基础上推注地塞米松进行治疗。比较两组治疗效果、产妇分娩中的心率血压情况、产妇产后出血和SI情况及不良反应发生情况。结果两组给药后0.5 h的收缩压、舒张压及心率都高于产前,差异有统计学意义(P<0.05);参照组产妇分娩后2 h内与2~24 h的平均出血量均高于研究组,差异有统计学意义(t=11.599、28.529,P<0.001)。参照组产妇的不良反应发生率为45.71%,高于研究组产妇的24.76%,差异有统计学意义(χ^(2)=10.099,P<0.001)。结论对于高危妊娠产妇采用地塞米松联合卡前列素氨丁三醇进行治疗,能够有效降低产妇产后的出血量,还能降低不良反应发生率,其安全性更加显著,值得广泛的应用。 Objective To study the effect of dexamethasone combined with carboprost tromethamine on postpartum hemorrhage in high-risk pregnant women.MethodsA total of 210 high-risk pregnant women admitted to the hospital from December 2016 to December 2018 were retrospectively selected as the research objects,and were divided into a study group and a reference group according to different treatment methods,with 105 cases in each.The reference group was treated with carboprost tromethamine for treatment,and the study group was treated with bolus injection of dexamethasone on the basis of the reference group.The treatment effects,heart rate,blood pressure,postpartum hemorrhage and SI,and adverse reactions were compared between the two groups.ResultsThe systolic blood pressure,diastolic blood pressure and heart rate at 0.5 h after administration in the two groups were higher than those before delivery,the difference was statistically significant(P<0.05);and the average blood loss of the reference group within 2 h and 2-24 h after delivery was higher than that in the study group,and the difference was statistically significant(t=11.599,28.529,P<0.001).The incidence of adverse reactions in the reference group was 45.71%,which was higher than 24.76% in the study group,the difference was statistically significant(χ~2=10.099,P<0.001).ConclusionDexamethasone combined with carboprost tromethamine can effectively reduce postpartum hemorrhage in highrisk pregnant women.And it can also reduce the probability of adverse reactions,its safety is more significant,and it is worthy of wide application.

作者何峰 HE Feng(Department of Obstetrics,Gaoqing County People's Hospital,Zibo,Shandong Province,256300 China)

机构地区高青县人民医院产科

出处《系统医学》 2022年第10期148-151,共4页 Systems Medicine

关键词高危妊娠地塞米松卡前列素氨丁三醇产后出血 High-risk pregnancy Dexamethasone Carboprost tromethamine Postpartum hemorrhage

分类号 R246.3 [医药卫生—针灸推拿学]

作者简介何峰(1971-),女,本科,副主任医师,研究方向为高危妊娠临床研究。