摘要
老年期痴呆是一种由脑部疾病所致的慢性或进行性影响记忆、思维、行为和日常活动能力的症候群,其首要病因是阿尔茨海默病(Alzheimer’s disease,AD),而轻度认知功能障碍(mild cognitive impairment,MCI)是老年期痴呆的高风险因素,目前药物治疗主要针对痴呆期患者,且不良反应较多,而非药物治疗与之相比,可以较安全有效的改善患者的认知功能。MCI的非药物治疗方法有很多,但目前尚无一个公认且规范的干预方案,本文对国内外MCI非药物治疗进行经验总结,为临床治疗和进一步研究提供参考。
Senile dementia is a brain disease that causes chronic or progressive effects on memory,thinking,behavior,and the ability to perform daily activities.The primary cause is Alzheimer’s disease,while mild cognitive impairment is a high risk factor for senile dementia.Compared with current drug therapy,which mainly targets at patients with dementia and has more side effects,non-drug therapy can improve patients’cognitive func tion more safely and effectively.There are many non-drug treatments for MCI,but there is currently no recognized and standardized intervention plan.This paper summarized the experience of non-drug treatment at home and abroad,and provides a reference for clinical treatment and further research.
作者
熊婷
唐旻
刘作良
XIONG Ting;TANG Min;LIU Zuoliang(Xiangya Third Hospital of Central South University,Changsha 410013,China)
出处
《中国实用神经疾病杂志》
2022年第3期368-375,共8页
Chinese Journal of Practical Nervous Diseases
基金
2019年湖南省保健专项资金科研课题(编号:XY050136)。
关键词
轻度认知障碍
老年人
阿尔茨海默病
非药物治疗
联合疗法
Mild cognitive impairment
Elderly
Alzheimer’s disease
Non-drug therapy
Combined treatment
作者简介
通信作者:刘作良,Email:iculzl@sina.com。