摘要
目的:观察针刀刺割、针刺联合持续气道正压通气(CPAP)治疗阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的临床疗效。方法:将60例OSAHS患者随机分为对照组、治疗组,每组30例,两组患者均给予戒烟戒酒、运动等饮食和生活干预。对照组患者予CPAP治疗,治疗组患者在对照组治疗基础上加用针刀刺割及针刺治疗。两组均连续治疗3个月后判定疗效,比较两组患者治疗前后的睡眠呼吸暂停低通气指数(AHI)、鼾声指数、最长呼吸暂停时间(LAT)、夜间最低氧饱和度(LSaO_(2))、血清白细胞介素-33(IL-33)、血清白细胞介素-37(IL-37)、生活质量测量量表(SF-36)评分。结果:治疗组总有效率为93.33%(28/30),对照组总有效率为76.67%(23/30);与治疗前比较,治疗后两组患者AHI、鼾声指数、LAT、IL-33、IL-37均降低(P<0.05),LSaO_(2)、SF-36评分均升高(P<0.05);治疗后两组比较,治疗组患者AHI、鼾声指数、LAT、IL-33、IL-37均低于对照组(P<0.05),LSaO_(2)、SF-36评分均高于对照组(P<0.05)。结论:针刀刺割、针刺联合CPAP能有效改善OSAHS患者的AHI、鼾声指数、LAT和LSaO_(2),降低炎症水平,提高OSAHS患者的生活质量。
Objective:To observe the clinical efficacy on needle knife puncture and acupuncture combined with continuous positive airway pressure ventilator(CPAP) in the treatment of obstructive sleep apnea hypopnea syndrome(OSAHS).Methods:A total of 60 patients with OSAHS in Weifang Hospital of traditional Chinese medicine were divided into control group and observation group by random number table,with 30 cases in each group.The patients in the control group were treated with CPAP,and the patients in the observation group were additionally treated with needle knife puncture and acupuncture on the basis of the treatment in the control group.The curative effect of the two groups was determined after 3 months of continuous treatment,the sleep apnea hypopnea index(AHI),snoring index,longest apnea time(LAT),nocturnal hypoxic saturation(LSaO_(2)),serum interleukin-33(IL-33),serum interleukin-37(IL-37) and quality of life scale(SF-36) were compared between the two groups before and after treatment.Results:The total effective rate of the observation group was 93.33%(28/30),and the total effective rate of the control group was 76.67%(23/30).Compared with before treatment,the AHI,snoring index,LAT,IL-33,IL-37 of the two groups decreased after treatment(P<0.05),and the scores of LSaO_(2)and SF-36 increased(P<0.05).The AHI,snoring index,LAT,IL-33 and IL-37 in the observation group were lower than those in the control group(P<0.05),and the scores of LSaO_(2)and SF-36 in the observation group were higher than those in the control group(P<0.05).Conclusion:Needle knife puncture and acupuncture combined with CPAP can effectively improve AHI,snoring index,LAT,and LSaO_(2)in patients with OSAHS,reduce the level of inflammation,and improve the life quality of patients with OSAHS.
作者
孙昭兰
张凤英
黄婷婷
相美玲
孙琳琳
吕艳春
SUN Zhao-lan;ZHANG Feng-ying;HUANG Ting-ting;Xiang Mei-ling;SUN Lin-lin;LYU Yan-chun(Shandong University of Traditional Chinese Medicine,Ji'nan Shandong 250000,China;Weifang Hospital of Traditional Chinese Medicine,Weifang Shandong 261000,China)
出处
《中医药导报》
2022年第4期49-52,61,共5页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
作者简介
通信作者:张凤英,E-mail:zhangfengying1979@163.com。
