摘要
Sex hormone-binding globulin(SHBG),a crucial modulator of sex steroids in human blood,regulates androgen bioavailability and homeostasis.1 When androgen or AR signaling is known to be involved in the hepatocellular carcinoma(HCC)and SHBG plays an integral role in regulating the levels of bioavailable androgens,the concern whether SHBG might influence HCC onset or progression by modulating androgen action remains open.
基金
This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education(No.2018R1D1A1A02043102 and 2021R1I1A2042991)
This work was supported by the National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT)(No.2021R1A4A1033078)
This work was supported by the NRF(National Research Foundation of Korea)Grant funded by the Korean Government(NRF-2019-Global Ph.D.Fellowship Program).
作者简介
Corresponding author:Eui-Ju Hong,Suite 401,Veterinary Medicine Bldg,College of Veterinary Medicine,99 Daehak-ro,Yuseong-gu,Daejeon 34134,Republic of Korea.E-mail address:ejhong@cnu.ac.kr。
